Gene Symbol | ARHGAP5 |
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Entrez Gene | 394 |
Alt Symbol | GFI2, RhoGAP5, p190-B, p190BRhoGAP |
Species | Human |
Gene Type | protein-coding |
Description | Rho GTPase activating protein 5 |
Other Description | growth factor independent 2|p100 RasGAP-associated p105 protein|p105 RhoGAP|rho GTPase-activating protein 5|rho-type GTPase-activating protein 5 |
Swissprots | D3DS89 Q05BU8 D3DS90 A1L376 Q59ER0 Q6DHZ3 A1L375 Q13017 A8KAA1 Q05BE8 |
Accessions | CCQ43130 EAW65935 EAW65936 EAW65937 EAW65938 Q13017 AB209751 BAD92988 AK023014 AK023468 AK292966 BAF85655 AK307454 AL045112 AY316523 AAP83192 BC032723 AAH32723 BC050059 AAH50059 BC075799 AAH75799 BC129928 AAI29929 BC129929 AAI29930 CA945100 U17032 AAA95963 XM_005267635 XP_005267692 XM_005267636 XP_005267693 NM_001030055 NP_001025226 NM_001173 NP_001164 |
Function | GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of RASA1/p120GAP. |
Subcellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Note=Also membrane-associated when found in fibrillar patterns that colocalize with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin. |
Tissue Specificity | Expressed in kidney, brain, liver and lung. |
Top Pathways | Focal adhesion, Leukocyte transendothelial migration |
Rho GAP p190-B CRISPR/Cas9 KO Plasmid (h) - sc-405755 from Santa Cruz Biotechnology
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Rho GAP p190-B HDR Plasmid (h) - sc-405755-HDR from Santa Cruz Biotechnology
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Rho GAP p190-B Double Nickase Plasmid (h) - sc-405755-NIC from Santa Cruz Biotechnology
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Rho GAP p190-B Double Nickase Plasmid (h2) - sc-405755-NIC-2 from Santa Cruz Biotechnology
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Rho GAP p190-B CRISPR Activation Plasmid (h) - sc-405755-ACT from Santa Cruz Biotechnology
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Rho GAP p190-B CRISPR Activation Plasmid (h2) - sc-405755-ACT-2 from Santa Cruz Biotechnology
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Rho GAP p190-B Lentiviral Activation Particles (h) - sc-405755-LAC from Santa Cruz Biotechnology
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Rho GAP p190-B Lentiviral Activation Particles (h2) - sc-405755-LAC-2 from Santa Cruz Biotechnology
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Rho GAP p190-B siRNA (h) - sc-44077 from Santa Cruz Biotechnology
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Rho GAP p190-B shRNA Plasmid (h) - sc-44077-SH from Santa Cruz Biotechnology
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Rho GAP p190-B shRNA (h) Lentiviral Particles - sc-44077-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU012431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3434 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3434 from Sigma-Aldrich
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ARHGAP5 siRNA (Human) - CRH0283 from Cohesion Biosciences
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RhoGAP RNAi - H00000394-R01 from Novus Biologicals
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RhoGAP RNAi - H00000394-R02 from Novus Biologicals
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ARHGAP5 - MBS8211853 from MyBioSource
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shRNA set against Human ARHGAP5(NM_001030055.1) - SHG069893 from Creative biogene
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shRNA set against Human ARHGAP5(NM_001173.2) - SHG070179 from Creative biogene
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Human ARHGAP5 siRNA - orb260785 from Biorbyt
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ARHGAP5 shRNA Plasmid (Human) - CHH0283 from Cohesion Biosciences
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ARHGAP5 miRNA 3'UTR clone - MiUTR1H-00524 from Creative biogene
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ARHGAP5 miRNA 3'UTR clone - MiUTR1H-00525 from Creative biogene
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