REG3A

Gene Symbol REG3A
Entrez Gene 5068
Alt Symbol HIP, HIP/PAP, INGAP, PAP, PAP-H, PAP1, PBCGF, REG-III, REG3
Species Human
Gene Type protein-coding
Description regenerating islet-derived 3 alpha
Other Description PAP homologous protein|REG-3-alpha|hepatocarcinoma-intestine-pancreas|hepatointestinal pancreatic protein|human proislet peptide|pancreatic beta cell growth factor|pancreatitis-associated protein 1|proliferation-inducing protein 34|proliferation-inducing protein 42|reg III-alpha|regenerating islet-derived protein 3-alpha|regenerating islet-derived protein III-alpha
Swissprots Q06141
Accessions AAA60020 AAX93047 BAA21104 CCQ43184 EAW99570 EAW99571 EAW99572 Q06141 AK291973 BAF84662 AK311523 AK311526 AY544128 AAT11159 AY544130 AAT11161 BC036776 AAH36776 BQ777112 D13510 BAA02728 DC300833 DQ890717 ABM81643 DQ893897 ABM84823 M84337 AAA36415 S51768 AAB24642 X68641 CAA48605 NM_002580 NP_002571 NM_138937 NP_620354 NM_138938 NP_620355
Function Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. {ECO:0000269|PubMed:16931762}.
Subcellular Location Secreted. Note=Found in the apical region of pancreatic acinar cells.
Tissue Specificity Highly expressed in epidermal keratinocytes of psoriasis patients (at protein level). Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis. {ECO:0000269|PubMed:1469087, ECO:0000269|PubMed:22727489}.

Reg IIIα (L-14) - sc-50969 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Reg IIIα (E-16) - sc-50967 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Reg IIIα/γ (B-10) - sc-377038 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Reg IIIα/γ (B-10): sc-377038. Western blot analysis of Reg IIIα/γ expression in human bladder tissue extract.

Reg IIIα/γ (H-69) - sc-134854 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Reg3a antibody - ab198824 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of paraffin-embedded human brain tissue labeling Reg3a using ab198824 at a 1/20 dilution.

Anti-Reg3a antibody - ab95316 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Reg3a antibody (ab95316) at 1/100 dilution (in TTBS/1% NFDM for 1 hr. at room temperature) + 293 cell line lysate at 35 µgSecondaryEnzyme-linked secondary antibody (typically horseradish peroxidase or alkaline phosphatase) in TTBS/1% NFDM for 30 min. at room temperature.

Anti-Reg3a antibody - ab134309 from Abcam

Prices $359.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Reg3a antibody - C-terminal - ab192224 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Reg3a antibody - C-terminal (ab192224) at 1/1000 dilution + Human pancreas tissue lysate at 35 µgSecondaryGoat anti-rabbit IgG H&L (HRP) at 1/5000 dilution

Anti-REG3A Antibody (aa129-163) - LS-C344236 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from human pancreas tissue lysate with REG3A Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

Anti-REG3A Antibody (aa27-175) - LS-C131816 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-REG3A Antibody (aa1-50) - LS-C144144 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-REG3A Antibody - LS-C38777 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-REG3A Antibody (aa19-48, AP) - LS-C268037 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-REG3A Antibody (aa19-48, APC) - LS-C268038 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-REG3A Antibody (aa19-48, Biotin) - LS-C268039 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-REG3A Antibody (aa19-48, FITC) - LS-C268040 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-REG3A Antibody (aa19-48, PE) - LS-C268044 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-REG3A Antibody (aa19-48, Azide-free, HRP) - LS-C268042 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-REG3A Antibody - LS-C285595 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-REG3A Antibody (aa43-92) - LS-C135250 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
REG3A antibody LS-C135250 Western blot of HeLa lysate.

Anti-REG3A Antibody (aa40-164, Biotin) - LS-C300717 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-REG3A Antibody (aa40-164, FITC) - LS-C302352 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-REG3A Antibody - LS-C193064 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of 293 cell lines, using REG3A antibody.

Anti-REG3A Antibody (aa40-164, FITC) - LS-C303162 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-REG3A Antibody (clone 2C11) - LS-C197844 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2C11
Detection limit for recombinant GST tagged REG3A is 3 ng/ml as a capture antibody.
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