| Gene Symbol |
DNER
|
| Entrez Gene |
92737
|
| Alt Symbol |
UNQ26, bet
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
delta/notch-like EGF repeat containing
|
| Other Description |
H_NH0150O02.1|WUGSC:H_NH0150O02.1|delta and Notch-like epidermal growth factor-related receptor|delta-notch-like EGF repeat-containing transmembrane
|
| Swissprots |
Q9UDM2 Q9NTF1 A6NP39 Q8NFT8 Q53R88 Q53TP7 Q8IYT0 Q8TB42 Q53TQ5
|
| Accessions |
AAF19247 AAY14680 AAY14939 AAY24263 EAW70892 EAW70893 EAW70894 EAW70895 Q8NFT8 AF442487 AAM21557 AK289553 BAF82242 AK304596 BAG65382 AK304631 BAG65411 AK308576 AL137311 CAB70690 AY358891 AAQ89250 BC024766 AAH24766 BC035009 AAH35009 DA115906 DA400901 XM_005246950 XP_005247007 NM_139072 NP_620711
|
| Function |
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Note=Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Expressed in brain, spinal cord and adrenal gland. {ECO:0000269|PubMed:11997712}.
|
![Western Blot: DNER Overexpression Lysate (Adult Normal) [NBP2-05608] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DNER.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10668_DNER%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05608-img0001.jpg)