Gene Symbol | DNER |
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Entrez Gene | 92737 |
Alt Symbol | UNQ26, bet |
Species | Human |
Gene Type | protein-coding |
Description | delta/notch-like EGF repeat containing |
Other Description | H_NH0150O02.1|WUGSC:H_NH0150O02.1|delta and Notch-like epidermal growth factor-related receptor|delta-notch-like EGF repeat-containing transmembrane |
Swissprots | Q9UDM2 Q9NTF1 A6NP39 Q8NFT8 Q53R88 Q53TP7 Q8IYT0 Q8TB42 Q53TQ5 |
Accessions | AAF19247 AAY14680 AAY14939 AAY24263 EAW70892 EAW70893 EAW70894 EAW70895 Q8NFT8 AF442487 AAM21557 AK289553 BAF82242 AK304596 BAG65382 AK304631 BAG65411 AK308576 AL137311 CAB70690 AY358891 AAQ89250 BC024766 AAH24766 BC035009 AAH35009 DA115906 DA400901 XM_005246950 XP_005247007 NM_139072 NP_620711 |
Function | Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Note=Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed in brain, spinal cord and adrenal gland. {ECO:0000269|PubMed:11997712}. |
Human DNER protein fragment - ab164917 from Abcam
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Human DNER protein fragment - ab108954 from Abcam
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Human DNER protein fragment - ab109042 from Abcam
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Mouse DNER protein fragment - ab109358 from Abcam
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DNER / BET Antibody Blocking Peptide - LS-E6655 from LifeSpan Bioscience
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DNER / BET Antibody Blocking Peptide - LS-E18330 from LifeSpan Bioscience
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DNER Partial Recombinant Protein - H00092737-Q01 from Novus Biologicals
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DNER-AntibodyC-term-Blocking-peptide - BP19467b from Abgent, a WuXi AppTec company
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Recombinant Human DNER Fc Chimera, CF - 3646-DN-050 from R&D Systems
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DNER Blocking Peptide - 33R-1844 from Fitzgerald
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BET Blocking Peptide - abx064284 from Abbexa
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Human dNER Protein - abx066302 from Abbexa
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DNER / BET - H00092737-Q01-10 from Acris Antibodies
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DNER / BET - H00092737-Q01-25 from Acris Antibodies
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Delta/Notch Like EGF Repeat Containing Protein - 20-9447 from ARP American Research Products
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DNER fusion protein - ag19973 from Proteintech Group
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DNER fusion protein - ag19955 from Proteintech Group
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Recombinant Human DNER, FLAG-tagged - DNER-26158TH from Creative Biomart
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Recombinant Human DNER, Fc-tagged - DNER-28368TH from Creative Biomart
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Recombinant Human DNER - DNER-835H from Creative Biomart
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Recombinant Human DNER, Fc Chimera - DNER-821H from Creative Biomart
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Recombinant Human Delta/notch-like EGF Repeat Containing, Fc Chimera - DNER-2080H from Creative Biomart
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Recombinant Delta/Notch Like EGF Repeat Containing Protein (dNER) - RPL146Hu01 from Uscn Life Science Inc.
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BET Blocking Peptide - CBP3090 from Cohesion Biosciences
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DNER (extracellular domain) - pro10185 from Covalab
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