Gene Symbol | DNER |
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Entrez Gene | 92737 |
Alt Symbol | UNQ26, bet |
Species | Human |
Gene Type | protein-coding |
Description | delta/notch-like EGF repeat containing |
Other Description | H_NH0150O02.1|WUGSC:H_NH0150O02.1|delta and Notch-like epidermal growth factor-related receptor|delta-notch-like EGF repeat-containing transmembrane |
Swissprots | Q9UDM2 Q9NTF1 A6NP39 Q8NFT8 Q53R88 Q53TP7 Q8IYT0 Q8TB42 Q53TQ5 |
Accessions | AAF19247 AAY14680 AAY14939 AAY24263 EAW70892 EAW70893 EAW70894 EAW70895 Q8NFT8 AF442487 AAM21557 AK289553 BAF82242 AK304596 BAG65382 AK304631 BAG65411 AK308576 AL137311 CAB70690 AY358891 AAQ89250 BC024766 AAH24766 BC035009 AAH35009 DA115906 DA400901 XM_005246950 XP_005247007 NM_139072 NP_620711 |
Function | Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Note=Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed in brain, spinal cord and adrenal gland. {ECO:0000269|PubMed:11997712}. |
DNER CRISPR/Cas9 KO Plasmid (h) - sc-407142 from Santa Cruz Biotechnology
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DNER HDR Plasmid (h) - sc-407142-HDR from Santa Cruz Biotechnology
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DNER Double Nickase Plasmid (h) - sc-407142-NIC from Santa Cruz Biotechnology
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DNER Double Nickase Plasmid (h2) - sc-407142-NIC-2 from Santa Cruz Biotechnology
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DNER CRISPR Activation Plasmid (h) - sc-407142-ACT from Santa Cruz Biotechnology
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DNER CRISPR Activation Plasmid (h2) - sc-407142-ACT-2 from Santa Cruz Biotechnology
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DNER Lentiviral Activation Particles (h) - sc-407142-LAC from Santa Cruz Biotechnology
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DNER Lentiviral Activation Particles (h2) - sc-407142-LAC-2 from Santa Cruz Biotechnology
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DNER siRNA (h) - sc-106901 from Santa Cruz Biotechnology
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DNER shRNA Plasmid (h) - sc-106901-SH from Santa Cruz Biotechnology
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DNER shRNA (h) Lentiviral Particles - sc-106901-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU046791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7395 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7395 from Sigma-Aldrich
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DNER siRNA (Human) - CRJ4162 from Cohesion Biosciences
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DNER RNAi - H00092737-R01 from Novus Biologicals
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DNER - MBS8220944 from MyBioSource
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shRNA set against Human DNER (NM_139072.3) - SHH279877 from Creative biogene
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shRNA set against Human DNER(NM_139072.3) - SHH011891 from Creative biogene
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DNER shRNA Plasmid (Human) - CHJ4162 from Cohesion Biosciences
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DNER miRNA 3'UTR clone - MiUTR1H-02936 from Creative biogene
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