Gene Symbol | Gm6484 |
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Entrez Gene | 624219 |
Alt Symbol | Angptl8, EG624219, Rifl |
Species | Mouse |
Gene Type | protein-coding |
Description | predicted gene 6484 |
Other Description | angiopoietin-like protein 8|betatrophin|hepatocellular carcinoma-associated protein TD26 homolog|lipasin|refeeding-induced fat and liver protein |
Swissprots | Q8R1L8 |
Accessions | Q8R1L8 BC024408 AAH24408 BC038127 BC051501 AAH51501 CK791522 KM253766 AIU96340 NM_001080940 NP_001074409 |
Function | Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577, PubMed:24043787). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (PubMed:24043787). According to a report, may act by promoting ANGPTL3 cleavage (PubMed:23150577). According to another study, not required for cleavage of ANGPTL3 (PubMed:24043787). {ECO:0000269|PubMed:22569073, ECO:0000269|PubMed:22809513, ECO:0000269|PubMed:23150577, ECO:0000269|PubMed:24043787}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:22569073, ECO:0000269|PubMed:23623304}. |
Tissue Specificity | Expressed in liver and fat. Enriched in white and brown adipose tissues. {ECO:0000269|PubMed:22569073, ECO:0000269|PubMed:22809513, ECO:0000269|PubMed:23623304}. |
EG624219 (Y-15) - sc-247690 from Santa Cruz Biotechnology
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Anti-ANGPTL8 / Betatrophin Antibody (FITC) - LS-C318138 from LifeSpan Bioscience
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Anti-ANGPTL8 / Betatrophin Antibody (HRP) - LS-C319023 from LifeSpan Bioscience
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Anti-ANGPTL8 / Betatrophin Antibody - LS-C319022 from LifeSpan Bioscience
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Anti-ANGPTL8 / TD26 Antibody (aa16-198) - LS-C315052 from LifeSpan Bioscience
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Betatrophin Antibody - abx109576 from Abbexa
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Betatrophin Antibody (Biotin) - abx105189 from Abbexa
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Betatrophin Antibody (FITC) - abx106606 from Abbexa
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Betatrophin Antibody (HRP) - abx108023 from Abbexa
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Betatrophin, Polyclonal Antibody - MBS1488710 from MyBioSource
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Betatrophin, Polyclonal Antibody - MBS1488967 from MyBioSource
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Betatrophin, Polyclonal Antibody - MBS1491347 from MyBioSource
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Betatrophin, Polyclonal Antibody - MBS1490128 from MyBioSource
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Angptl8 Antibody,Biotin conjugated - CSB-PA844436LD01MO from Cusabio
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Angptl8 Antibody,FITC conjugated - CSB-PA844436LC01MO from Cusabio
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Angptl8 Antibody,HRP conjugated - CSB-PA844436LB01MO from Cusabio
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Angptl8 Antibody - CSB-PA844436LA01MO from Cusabio
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Polyclonal Antibody to Angiopoietin Like Protein 8 (ANGPTL8) - PAW803Mu01 from Cloud-clone
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Polyclonal Antibody to Angiopoietin Like Protein 8 (ANGPTL8) - PAW803Mu02 from Cloud-clone
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Betatrophin antibody - orb240858 from Biorbyt
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