| Gene Symbol |
BTN2A2
|
| Entrez Gene |
10385
|
| Alt Symbol |
BT2.2, BTF2, BTN2.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
butyrophilin, subfamily 2, member A2
|
| Other Description |
butyrophilin 2|butyrophilin subfamily 2 member A2
|
| Swissprots |
A6NM84 B4DQ01 O00480 Q8WVV5 E9PH07 B4DE97
|
| Accessions |
EAW55561 EAW55562 EAW55563 EAW55564 EAW55565 Q8WVV5 AK123902 AK289883 BAF82572 AK293526 BAG57008 AK298570 BAG60763 AK304744 BAG65503 BC013258 BC014021 AAH14021 BC017497 AAH17497 BI754184 BP234194 DC373063 DC388932 U90550 AAB53428 XM_005248797 XP_005248854 XM_005248798 XP_005248855 XM_006714953 XP_006715016 XM_006714954 XP_006715017 XM_006714955 XP_006715018 XM_011514228 XP_011512530 XM_011514229 XP_011512531 XM_011514230 XP_011512532 XM_011514231 XP_011512533 NM_001197237 NP_001184166 NM_001197238 NP_001184167 NM_001197239 NP_001184168 NM_001197240 NP_001184169 NM_006995 NP_008926 NM_181531 NP_853509
|
| Function |
Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney. {ECO:0000269|PubMed:9149941}.
|