Gene Symbol | BTN2A2 |
---|---|
Entrez Gene | 10385 |
Alt Symbol | BT2.2, BTF2, BTN2.2 |
Species | Human |
Gene Type | protein-coding |
Description | butyrophilin, subfamily 2, member A2 |
Other Description | butyrophilin 2|butyrophilin subfamily 2 member A2 |
Swissprots | A6NM84 B4DQ01 O00480 Q8WVV5 E9PH07 B4DE97 |
Accessions | EAW55561 EAW55562 EAW55563 EAW55564 EAW55565 Q8WVV5 AK123902 AK289883 BAF82572 AK293526 BAG57008 AK298570 BAG60763 AK304744 BAG65503 BC013258 BC014021 AAH14021 BC017497 AAH17497 BI754184 BP234194 DC373063 DC388932 U90550 AAB53428 XM_005248797 XP_005248854 XM_005248798 XP_005248855 XM_006714953 XP_006715016 XM_006714954 XP_006715017 XM_006714955 XP_006715018 XM_011514228 XP_011512530 XM_011514229 XP_011512531 XM_011514230 XP_011512532 XM_011514231 XP_011512533 NM_001197237 NP_001184166 NM_001197238 NP_001184167 NM_001197239 NP_001184168 NM_001197240 NP_001184169 NM_006995 NP_008926 NM_181531 NP_853509 |
Function | Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney. {ECO:0000269|PubMed:9149941}. |