Gene Symbol | BTN2A2 |
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Entrez Gene | 10385 |
Alt Symbol | BT2.2, BTF2, BTN2.2 |
Species | Human |
Gene Type | protein-coding |
Description | butyrophilin, subfamily 2, member A2 |
Other Description | butyrophilin 2|butyrophilin subfamily 2 member A2 |
Swissprots | A6NM84 B4DQ01 O00480 Q8WVV5 E9PH07 B4DE97 |
Accessions | EAW55561 EAW55562 EAW55563 EAW55564 EAW55565 Q8WVV5 AK123902 AK289883 BAF82572 AK293526 BAG57008 AK298570 BAG60763 AK304744 BAG65503 BC013258 BC014021 AAH14021 BC017497 AAH17497 BI754184 BP234194 DC373063 DC388932 U90550 AAB53428 XM_005248797 XP_005248854 XM_005248798 XP_005248855 XM_006714953 XP_006715016 XM_006714954 XP_006715017 XM_006714955 XP_006715018 XM_011514228 XP_011512530 XM_011514229 XP_011512531 XM_011514230 XP_011512532 XM_011514231 XP_011512533 NM_001197237 NP_001184166 NM_001197238 NP_001184167 NM_001197239 NP_001184168 NM_001197240 NP_001184169 NM_006995 NP_008926 NM_181531 NP_853509 |
Function | Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney. {ECO:0000269|PubMed:9149941}. |
BTN2A2 CRISPR/Cas9 KO Plasmid (h) - sc-417653 from Santa Cruz Biotechnology
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BTN2A2 HDR Plasmid (h) - sc-417653-HDR from Santa Cruz Biotechnology
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BTN2A2 Double Nickase Plasmid (h) - sc-417653-NIC from Santa Cruz Biotechnology
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BTN2A2 Double Nickase Plasmid (h2) - sc-417653-NIC-2 from Santa Cruz Biotechnology
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BTN2A2 CRISPR Activation Plasmid (h) - sc-417653-ACT from Santa Cruz Biotechnology
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BTN2A2 CRISPR Activation Plasmid (h2) - sc-417653-ACT-2 from Santa Cruz Biotechnology
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BTN2A2 Lentiviral Activation Particles (h) - sc-417653-LAC from Santa Cruz Biotechnology
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BTN2A2 Lentiviral Activation Particles (h2) - sc-417653-LAC-2 from Santa Cruz Biotechnology
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BTN2A2 siRNA (h) - sc-95423 from Santa Cruz Biotechnology
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BTN2A2 shRNA Plasmid (h) - sc-95423-SH from Santa Cruz Biotechnology
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BTN2A2 shRNA (h) Lentiviral Particles - sc-95423-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU115711 from Sigma-Aldrich
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MISSION® esiRNA - EHU078501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4110 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4110 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10720 from Sigma-Aldrich
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BTN2A2 siRNA (Human) - CRH7036 from Cohesion Biosciences
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BTN2A2 - MBS8221136 from MyBioSource
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shRNA set against Human BTN2A2 (NM_181531.2) - SHH248334 from Creative biogene
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Human BTN2A2 siRNA - orb267538 from Biorbyt
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BTN2A2 shRNA Plasmid (Human) - CHH7036 from Cohesion Biosciences
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BTN2A2 miRNA 3'UTR clone - MiUTR3H-12964 from Creative biogene
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BTN2A2 miRNA 3'UTR clone - MiUTR3H-12965 from Creative biogene
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