SH2D4A

Gene Symbol SH2D4A
Entrez Gene 63898
Alt Symbol PPP1R38, SH2A
Species Human
Gene Type protein-coding
Description SH2 domain containing 4A
Other Description SH2 domain-containing protein 4A|protein SH(2)A|protein phosphatase 1 regulatory subunit 38|protein phosphatase 1, regulatory subunit 38
Swissprots Q5XKC1 B4DDR1 Q9H7F7 Q6NXE9 Q96C88 Q86YM2 Q9H788
Accessions EAW63773 Q9H788 AK024620 BAB14935 AK024799 BAB15010 AK225052 AK293301 BAG56822 AY190323 AAO41715 BC014525 AAH14525 BC067117 AAH67117 BC082982 AAH82982 CA418381 DA952240 XM_011544610 XP_011542912 XM_011544611 XP_011542913 NM_001174159 NP_001167630 NM_001174160 NP_001167631 NM_022071 NP_071354
Function Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. {ECO:0000269|PubMed:18641339, ECO:0000269|PubMed:19712589}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18641339}. Note=Located at podocyte foot processes. {ECO:0000250}.
Tissue Specificity Ubiquitously expressed. Aberrantly expressed in some cancers. {ECO:0000269|PubMed:12476414}.

SH2D4A (F-5) - sc-514170 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SH2D4A (F-5): sc-514170. Western blot analysis of SH2D4A expression in HeLa (A) and RT-4 (B) whole cell lysates.

SH2D4A (S-16) - sc-98126 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SH2D4A (S-16): sc-98126. Western blot analysis of SH2D4A expression in KNRK nuclear extract.

SH2D4A (P-16) - sc-98125 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SH2D4A (63-J) - sc-100288 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
SH2D4A (63-J): sc-100288. Western blot analysis of SH2D4A expression in HeLa whole cell lysate.

Anti-SH2D4A antibody - ab103166 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of normal liver (left) and hepatocellular carcinoma (right) labelling SH2D4A with ab103166 at 1/200. Magnification: 400X. Representative pictures of different protein levels for SH2D4A.

Anti-SH2D4A antibody - ab201289 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SH2D4A antibody (ab201289)Lane 1 : HEK293T whole cell lsyateLane 2 : Raw 264.7 whole cell lsyateLane 3 : PC12 whole cell lsyate

Anti-SH2D4A antibody - ab67249 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-SH2D4A antibody (ab67249) at 1/500 dilution + human liver tissue lysate at 25 µg/mlSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-SH2D4A antibody - ab80606 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-SH2D4A antibody (ab80606) at 0.1 µg/ml + Human Kidney lysate (in RIPA buffer) at 35 µg

Anti-SH2D4A antibody - ab110969 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab110969 at 1/50 dilution staining SH2D4A in paraffin-embedded Human Lung carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-SH2D4A antibody - N-terminal - ab170797 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin/PFA-fixed paraffin-embedded Human kidney tissue labeling SH2D4A with ab170797 at a 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

Anti-SH2D4A Antibody (aa38-67, AP) - LS-C240734 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH2D4A Antibody (aa38-67, APC) - LS-C240735 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH2D4A Antibody (aa38-67, Biotin) - LS-C240736 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH2D4A Antibody (aa38-67, FITC) - LS-C240737 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH2D4A Antibody (aa38-67, PE) - LS-C240739 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH2D4A Antibody (aa38-67, Azide-free, HRP) - LS-C248150 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH2D4A Antibody (aa180-220) - LS-C291389 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SH2D4A Antibody (aa45-75) - LS-C325078 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH2D4A Antibody (aa239-338, Azide-free) - LS-C328652 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-SH2D4A Antibody (aa145-194) IHC-plus™ - LS-B8272 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SH2D4A antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8272 dilution 5-10 ug/ml.

Anti-SH2D4A Antibody (aa152-164) - LS-C87384 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.1 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

Anti-SH2D4A Antibody (aa38-67) - LS-C169056 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SH2D4A Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-SH2D4A Antibody (clone 3G8) - LS-C133802 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G8
Immunoperoxidase of monoclonal antibody to SH2D4A on formalin-fixed paraffin-embedded human lung. [antibody concentration 3 ug/ml]

SH2D4A Antibody (3G8) - H00063898-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G8
Western Blot: SH2D4A Antibody (3G8) [H00063898-M01] - SH2D4A monoclonal antibody (M01), clone 3G8 Analysis of SH2D4A expression in HeLa.

SH2D4A Antibody - NBP1-82158 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SH2D4A Antibody [NBP1-82158] - Lane 1: Marker [kDa] 219, 112, 85, 49, 32, 25, 18. Lane 2: Human cell line RT-4
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