FSCN1

Gene Symbol FSCN1
Entrez Gene 6624
Alt Symbol FAN1, HSN, SNL, p55
Species Human
Gene Type protein-coding
Description fascin actin-bundling protein 1
Other Description 55 kDa actin-bundling protein|fascin|fascin homolog 1, actin-bundling protein|singed-like (fascin homolog, sea urchin)
Swissprots Q9BRF1 B2RE97 Q96IH1 A6NI89 Q96IC5 Q16658
Accessions AAL01526 CBX47601 EAW87344 EAW87345 EAW87346 Q16658 AK095254 BAG53015 AK095830 BAG53141 AK125295 AK316607 BAG38194 BC000521 AAH00521 BC006304 AAH06304 BC007539 AAH07539 BC007643 AAH07643 BC007948 AAH07948 BC007988 AAH07988 BI546742 BT006636 AAP35282 BU629782 DQ891402 ABM82328 DQ894580 ABM85506 U03057 AAA86442 U09873 AAA62201 NM_003088 NP_003079
Function Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. {ECO:0000269|PubMed:20137952, ECO:0000269|PubMed:20393565, ECO:0000269|PubMed:9362073, ECO:0000269|PubMed:9571235}.
Subcellular Location Cytoplasm, cytoskeleton. Cell projection, filopodium. Cell projection, invadopodium. Cytoplasm, cytosol. Note=In glioma cells, partially colocalizes with F-actin stress fibers in the cytosol.
Tissue Specificity Ubiquitous.
Top Pathways MicroRNAs in cancer

Fascin 1 CRISPR/Cas9 KO Plasmid (h) - sc-402535 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fascin 1 HDR Plasmid (h) - sc-402535-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fascin 1 Double Nickase Plasmid (h) - sc-402535-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fascin 1 Double Nickase Plasmid (h2) - sc-402535-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fascin 1 CRISPR Activation Plasmid (h) - sc-402535-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fascin 1 CRISPR Activation Plasmid (h2) - sc-402535-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fascin 1 Lentiviral Activation Particles (h) - sc-402535-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fascin 1 Lentiviral Activation Particles (h2) - sc-402535-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fascin 1 siRNA (h) - sc-35359 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fascin 1 shRNA Plasmid (h) - sc-35359-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fascin 1 shRNA (h) Lentiviral Particles - sc-35359-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU050541 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8961 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8961 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08639 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08639

FSCN1 siRNA (Human) - CRH4507 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FSCN1 - MBS8213801 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FSCN1 (NM_003088.3) - SHH297313 from Creative biogene

Category siRNA
Species Reactivities Human

Human FSCN1 siRNA - orb265009 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FSCN1 shRNA Plasmid (Human) - CHH4507 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FSCN1 miRNA 3'UTR clone - MiUTR3H-05231 from Creative biogene

Species Reactivities Human
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