| Gene Symbol |
GRIN2A
|
| Entrez Gene |
2903
|
| Alt Symbol |
EPND, FESD, GluN2A, LKS, NMDAR2A, NR2A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
|
| Other Description |
N-methyl D-aspartate receptor subtype 2A|N-methyl-D-aspartate receptor channel, subunit epsilon-1|N-methyl-D-aspartate receptor subunit 2A|glutamate receptor ionotropic, NMDA 2A
|
| Swissprots |
O00669 Q17RZ6 Q12879
|
| Accessions |
AAN75825 EAW85187 Q12879 AB209695 BAD92932 AK124698 AK295620 BAG58499 AK308862 BC117131 AAI17132 BC143273 AAI43274 CR749843 HG507717 HQ258685 ADR83436 R43097 U07199 U09002 AAB60343 U90277 AAB49992 XM_011522456 XP_011520758 XM_011522457 XP_011520759 XM_011522458 XP_011520760 XM_011522459 XP_011520761 XM_011522460 XP_011520762 XM_011522461 XP_011520763 NM_000833 NP_000824 NM_001134407 NP_001127879 NM_001134408 NP_001127880
|
| Function |
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Rap1 signaling pathway, Circadian entrainment, Alcoholism, Cocaine addiction, cAMP signaling pathway
|