GRIN2A

Gene Symbol GRIN2A
Entrez Gene 2903
Alt Symbol EPND, FESD, GluN2A, LKS, NMDAR2A, NR2A
Species Human
Gene Type protein-coding
Description glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Other Description N-methyl D-aspartate receptor subtype 2A|N-methyl-D-aspartate receptor channel, subunit epsilon-1|N-methyl-D-aspartate receptor subunit 2A|glutamate receptor ionotropic, NMDA 2A
Swissprots O00669 Q17RZ6 Q12879
Accessions AAN75825 EAW85187 Q12879 AB209695 BAD92932 AK124698 AK295620 BAG58499 AK308862 BC117131 AAI17132 BC143273 AAI43274 CR749843 HG507717 HQ258685 ADR83436 R43097 U07199 U09002 AAB60343 U90277 AAB49992 XM_011522456 XP_011520758 XM_011522457 XP_011520759 XM_011522458 XP_011520760 XM_011522459 XP_011520761 XM_011522460 XP_011520762 XM_011522461 XP_011520763 NM_000833 NP_000824 NM_001134407 NP_001127879 NM_001134408 NP_001127880
Function NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Top Pathways Rap1 signaling pathway, Circadian entrainment, Alcoholism, Cocaine addiction, cAMP signaling pathway

All lanes : Anti-NMDAR2A (phospho Y1325) antibody ( ab16646 ) at 1 µg/ml Lane 1 : mouse brain lysate Lane 2 : mouse brain lysate with Mouse NMDAR2A (phospho Y1325) peptide (ab16985) at 1 µg/ml Lane 3 : mouse brain lysate with Mouse NMDAR2A peptide ( ab16990 ) at 1 µg/ml Lysates/proteins at 20 µg per lane. Performed under reducing conditions. Predicted band size : 163 kDa Observed band size : 163 kDa Additional bands at : 50 kDa (possible non-specific secondary antibody binding),~130 kDa,~150 kDa. We are unsure as to the identity of these extra bands. Exposure time : 5 minutes Chris Anderson, Wellcome Trust Sanger Institute, United Kingdom
All lanes : Anti-NMDAR2A (phospho Y1387) antibody ( ab16647 ) at 1 µg/ml Lane 1 : mouse brain lysate Lane 2 : mouse brain lysate with Mouse NMDAR2A (phospho Y1387) peptide (ab16984) at 1 µg/ml Lane 3 : mouse brain lysate with Mouse NMDAR2A peptide ( ab16989 ) Lysates/proteins at 20 µg per lane. Performed under reducing conditions. Predicted band size : 163 kDa Observed band size : 163 kDa Additional bands at : ~130 kDa,~150 kDa. We are unsure as to the identity of these extra bands. Exposure time : 5 minutes Chris Anderson, Wellcome Trust Sanger Institute, United Kingdom

Mouse NMDAR2A peptide - ab16989 from Abcam

Category Peptide
All lanes : Anti-NMDAR2A (phospho Y1387) antibody ( ab16647 ) at 1 µg/ml Lane 1 : mouse brain lysate Lane 2 : mouse brain lysate with Mouse NMDAR2A (phospho Y1387) peptide ( ab16984 ) at 1 µg/ml Lane 3 : mouse brain lysate with Mouse NMDAR2A peptide (ab16989) Lysates/proteins at 20 µg per lane. Performed under reducing conditions. Predicted band size : 163 kDa Observed band size : 163 kDa Additional bands at : ~130 kDa,~150 kDa. We are unsure as to the identity of these extra bands. Exposure time : 5 minutes Chris Anderson, Wellcome Trust Sanger Institute, United Kingdom

Mouse NMDAR2A peptide - ab16990 from Abcam

Category Peptide
All lanes : Anti-NMDAR2A (phospho Y1325) antibody ( ab16646 ) at 1 µg/ml Lane 1 : mouse brain lysate Lane 2 : mouse brain lysate with Mouse NMDAR2A (phospho Y1325) peptide ( ab16985 ) at 1 µg/ml Lane 3 : mouse brain lysate with Mouse NMDAR2A peptide (ab16990) at 1 µg/ml Lysates/proteins at 20 µg per lane. Performed under reducing conditions. Predicted band size : 163 kDa Observed band size : 163 kDa Additional bands at : 50 kDa (possible non-specific secondary antibody binding),~130 kDa,~150 kDa. We are unsure as to the identity of these extra bands. Exposure time : 5 minutes Chris Anderson, Wellcome Trust Sanger Institute, United Kingdom

Mouse NMDAR2A peptide - ab16994 from Abcam

Category Peptide
ELISA using ab16644 . The blue line indicates binding to the NMDAR2A phospho Y1292 immunising peptide ( ab16993 ). Binding to a peptide with an unmodified Y1292 residue ( ab16694 ) was greatly reduced (green line). This indicates that ab16644 is specific for the modified peptide.

NMDAR2A peptide - ab176410 from Abcam

Category Peptide

GRIN2A / NMDAR2A / NR2A Antibody Blocking Peptide - LS-E927 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GRIN2A / NMDAR2A / NR2A Antibody Blocking Peptide - LS-E958 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GRIN2A / NMDAR2A / NR2A Antibody Blocking Peptide - LS-E12472 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GRIN2A-Antibody-C-term-Blocking-peptide - BP11390b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

GRIN2A-Antibody-Center-Blocking-peptide - BP11331c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant human Glutamate [NMDA] receptor subunit epsilon-1 (OPCA01013) - OPCA01013 from Aviva Systems Biology

Category Protein
Prices $220.00
Sizes 50 µg
Species Human

Human GRIN2A protein - orb245579 from Biorbyt

Category Protein
Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00
Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg
Species Human

GRIN2A Blocking Peptide - 33R-2020 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Recombinant Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A) - RPE806Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A) - RPE806Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A) - RPE806Mu02 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 2A (GRIN2A) - RPE806Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant human Glutamate [NMDA] receptor subunit epsilon-1 - CSB-EP141294h CSB-BP141294h CSB-MP141294h from Cusabio

Category Protein
Source E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human Glutamate [NMDA] receptor subunit epsilon-1(GRIN2A) ,partial - CSB-YP618634HU CSB-EP618634HU CSB-BP618634HU CSB-MP618634HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

GRIN2A Peptide, Human - M34GP06659H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

PDZ domain scaffold protein anti-Human NMDA receptor NR2 subunits - SPD-L169 from Creative Biolabs

Category Protein
Source E. coli
Species Human

PDZ domain scaffold protein anti-Human N-methyl-D-aspartate (NMDA) receptor - SPD-L170 from Creative Biolabs

Category Protein
Source E. coli
Species Human

GRIN2A Recombinant Protein (OPCD03681) - OPCD03681 from Aviva Systems Biology

Category Protein
Source E.coli
Species Human
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