Gene Symbol | GRIN2A |
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Entrez Gene | 2903 |
Alt Symbol | EPND, FESD, GluN2A, LKS, NMDAR2A, NR2A |
Species | Human |
Gene Type | protein-coding |
Description | glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
Other Description | N-methyl D-aspartate receptor subtype 2A|N-methyl-D-aspartate receptor channel, subunit epsilon-1|N-methyl-D-aspartate receptor subunit 2A|glutamate receptor ionotropic, NMDA 2A |
Swissprots | O00669 Q17RZ6 Q12879 |
Accessions | AAN75825 EAW85187 Q12879 AB209695 BAD92932 AK124698 AK295620 BAG58499 AK308862 BC117131 AAI17132 BC143273 AAI43274 CR749843 HG507717 HQ258685 ADR83436 R43097 U07199 U09002 AAB60343 U90277 AAB49992 XM_011522456 XP_011520758 XM_011522457 XP_011520759 XM_011522458 XP_011520760 XM_011522459 XP_011520761 XM_011522460 XP_011520762 XM_011522461 XP_011520763 NM_000833 NP_000824 NM_001134407 NP_001127879 NM_001134408 NP_001127880 |
Function | NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
Top Pathways | Rap1 signaling pathway, Circadian entrainment, Alcoholism, Cocaine addiction, cAMP signaling pathway |
NMDAε1 siRNA (h) - sc-36083 from Santa Cruz Biotechnology
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NMDAε1 shRNA Plasmid (h) - sc-36083-SH from Santa Cruz Biotechnology
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NMDAε1 shRNA (h) Lentiviral Particles - sc-36083-V from Santa Cruz Biotechnology
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NMDAR2A RNAi - H00002903-R01 from Novus Biologicals
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MISSION® esiRNA - EHU040271 from Sigma-Aldrich
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MISSION® esiRNA - EHU036291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9685 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9685 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12714 from Sigma-Aldrich
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GRIN2A siRNA (Human) - CRH1957 from Cohesion Biosciences
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GRIN2A - MBS8240427 from MyBioSource
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shRNA set against Human GRIN2A (NM_000833.3) - SHH307898 from Creative biogene
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GRIN2A shRNA Plasmid (Human) - CHH1957 from Cohesion Biosciences
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GRIN2A miRNA 3'UTR clone - MiUTR3H-00895 from Creative biogene
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