GALNT3

Gene Symbol	GALNT3
Entrez Gene	2591
Alt Symbol	GalNAc-T3, HFTC, HHS
Species	Human
Gene Type	protein-coding
Description	polypeptide N-acetylgalactosaminyltransferase 3
Other Description	GalNAc transferase 3|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)|polypeptide GalNAc transferase 3|polypeptide GalNAc-transferase T3|pp-GaNTase 3|protein-UDP acetylgalactosaminyltransferase 3
Swissprots	Q53TG9 Q7Z476 Q14435
Accessions	AAY14678 EAX11323 EAX11324 Q14435 AJ505954 CAD44536 AK307391 AK313389 BAG36187 BC056246 AAH56246 BC113565 AAI13566 BC113567 AAI13568 BU567493 BX094158 BX647473 DB098143 DB727693 HQ258332 ADR83086 X92689 CAA63371 XM_005246449 XP_005246506 XM_006712402 XP_006712465 XM_011510929 XP_011509231 NM_004482 NP_004473
Function	Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. Plays a central role in phosphate homeostasis. {ECO:0000269|PubMed:16638743, ECO:0000269|PubMed:9295285}.
Subcellular Location	Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:9394011}; Single-pass type II membrane protein {ECO:0000269|PubMed:9394011}. Note=Resides preferentially in the trans and medial parts of the Golgi stack.
Tissue Specificity	Expressed in organs that contain secretory epithelial glands. Highly expressed in pancreas, skin, kidney and testis. Weakly expressed in prostate, ovary, intestine and colon. Also expressed in placenta and lung and fetal lung and fetal kidney. {ECO:0000269|PubMed:12708471, ECO:0000269|PubMed:8663203}.
Top Pathways	Mucin type O-Glycan biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GALNT3 full length protein - ab158494 from Abcam Category Protein Source Wheat germ Species Human

Human GALNT3 protein fragment - ab158495 from Abcam Category Protein Source Wheat germ Species Human

Human GALNT3 protein fragment - ab199572 from Abcam Category Protein Source HEK 293 cells Species Human

GALNT3 Antibody Blocking Peptide - LS-E16936 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GALNT3 Antibody Blocking Peptide - LS-E10005 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Polypeptide GalNac Transferase 3/GALNT3 Protein - H00002591-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Polypeptide GalNac Transferase 3/GALNT3 Protein - H00002591-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GALNT3-Antibody-Center-Blocking-Peptide - BP9208c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human GALNT3, CF - 7174-GT-020 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Gln38-Asp633, with N-terminal CD33 signal sequence and 6-His tag

Galnt3 Blocking Peptide - 33R-7061 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GALNT3 - H00002591-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GALNT3 - H00002591-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GALNT3 - H00002591-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GALNT3 - H00002591-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GALNT3 fusion protein - ag10140 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GALNT3 fusion protein - Ag9941 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human UDP-N-acetyl-Alpha-D-Galactosamine: Polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3), His-tagged - GALNT3-601H from Creative Biomart Category Protein Source Murine myeloma cellline, NS0-derived.

Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 3(GALNT3) - CSB-YP613501HU CSB-EP613501HU CSB-BP613501HU CSB-MP613501HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human GALNT3 Protein, CF - 7174-GT from R&D Systems Category Protein Prices $359.00 Sizes 20 µg Source Mouse myeloma cell line, NS0-derived Gln38-Asp633, with N-terminal CD33 signal sequence and 6-His tag Species Human

Human Polypeptide N-Acetylgalactosaminyltransferase 3 protein (C-His) - orb311940 from Biorbyt Category Protein Prices $366.00, $629.00, $2,032.00, $3,137.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Polypeptide GalNac Transferase 3/GALNT3 Recombinant Protein Antigen - NBP1-81849PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GALNT3 Peptide, Human - M34GP06081H from Creative Peptides Category Peptide Source Synthetic. Species Human

Polypeptide GalNac Transferase 3 Recombinant Protein - 92-355 from ProSci Category Protein Prices $575.00 Sizes 50 µg Source Human Cells Species Human

GALNT3, Recombinant Protein - MBS8249088 from MyBioSource Category Protein Prices $255.00, $635.00, $2,370.00 Sizes 10 µg, 50 µg, 500 µg Source Human cells Species Human

GalNAc-T3, soluble fragment, Human Recombinant - P1216 from Biovision Category Protein Prices $175.00 Sizes 5 μg Source Insect cells Species Human

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