GALNT3

Gene Symbol GALNT3
Entrez Gene 2591
Alt Symbol GalNAc-T3, HFTC, HHS
Species Human
Gene Type protein-coding
Description polypeptide N-acetylgalactosaminyltransferase 3
Other Description GalNAc transferase 3|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)|polypeptide GalNAc transferase 3|polypeptide GalNAc-transferase T3|pp-GaNTase 3|protein-UDP acetylgalactosaminyltransferase 3
Swissprots Q53TG9 Q7Z476 Q14435
Accessions AAY14678 EAX11323 EAX11324 Q14435 AJ505954 CAD44536 AK307391 AK313389 BAG36187 BC056246 AAH56246 BC113565 AAI13566 BC113567 AAI13568 BU567493 BX094158 BX647473 DB098143 DB727693 HQ258332 ADR83086 X92689 CAA63371 XM_005246449 XP_005246506 XM_006712402 XP_006712465 XM_011510929 XP_011509231 NM_004482 NP_004473
Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. Plays a central role in phosphate homeostasis. {ECO:0000269|PubMed:16638743, ECO:0000269|PubMed:9295285}.
Subcellular Location Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:9394011}; Single-pass type II membrane protein {ECO:0000269|PubMed:9394011}. Note=Resides preferentially in the trans and medial parts of the Golgi stack.
Tissue Specificity Expressed in organs that contain secretory epithelial glands. Highly expressed in pancreas, skin, kidney and testis. Weakly expressed in prostate, ovary, intestine and colon. Also expressed in placenta and lung and fetal lung and fetal kidney. {ECO:0000269|PubMed:12708471, ECO:0000269|PubMed:8663203}.
Top Pathways Mucin type O-Glycan biosynthesis

GalNAc-T3 (C-14) - sc-68515 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GalNAc-T3 (C-14): sc-68515. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of exocrine glandular cells and Islets of Langerhans.

GalNAc-T3 (E-17) - sc-68516 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GalNAc-T3 (E-17): sc-68516. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of exocrine glandular cells and Islets of Langerhans.

GalNAc-T3 (H-68) - sc-292250 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

GalNAc-T3 (I-17) - sc-68517 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GalNAc-T3 (I-17): sc-68517. Western blot analysis of GalNAc-T3 expression in MCF7 (A), COLO 205 (B) and HeLa (C) whole cell lysates.

GalNAc-T3 (N-14) - sc-68518 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-GALNT3 antibody - ab95314 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GALNT3 antibody (ab95314) at 1/100 dilution + MCF7 cell line lysates at 35 µg

Anti-GALNT3 antibody - ab67590 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-GALNT3 antibody (ab67590) at 1/500 dilutionLane 1 : GALNT3 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP conjugated secondary antibody at 1/2500 dilution

Anti-GALNT3 Antibody (aa454-481, AP) - LS-C257540 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT3 Antibody (aa454-481, APC) - LS-C259456 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT3 Antibody (aa454-481, Biotin) - LS-C259458 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT3 Antibody (aa454-481, FITC) - LS-C259459 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT3 Antibody (aa454-481, Azide-free, HRP) - LS-C259460 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT3 Antibody (aa454-481, PE) - LS-C259461 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT3 Antibody - LS-C307652 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GALNT3 Antibody (aa461-490) - LS-C321542 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GALNT3 Antibody - LS-C310440 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GALNT3 Antibody (aa93-142) - LS-C135192 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GALNT3 antibody LS-C135192 Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml.

Anti-GALNT3 Antibody - LS-C334817 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using GALNT3 antibody.

Anti-GALNT3 Antibody (aa454-481) - LS-C166355 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human skin tissue reacted with GALNT3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Polypeptide GalNac Transferase 3/GALNT3 Antibody - AF7174 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Polypeptide GalNac Transferase 3/GALNT3 was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line using Sheep Anti-Human Polypeptide GalNac Transferase 3/GALNT3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7174) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red; Catalog # NL010) and counterstained with DAPI (blue). Specific staining was localized to Golgi granules. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Polypeptide GalNac Transferase 3/GALNT3 Antibody - NBP1-74244 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-74244] - Titration: 1.0 ug/ml Positive Control: Rat Brain.

Polypeptide GalNac Transferase 3/GALNT3 Antibody - NBP1-81849 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-81849] - Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.

Polypeptide GalNac Transferase 3/GALNT3 Antibody - H00002591-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: GALNT3 Antibody [H00002591-B01] - analysis of GALNT3 expression in transfected 293T cell line by GALNT3 MaxPab polyclonal antibody (B01). Lane 1: GALNT3 transfected lysate (15.90 KDa). Lane 2: Non-transfected lysate.

Polypeptide GalNac Transferase 3/GALNT3 Antibody - H00002591-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Polypeptide GalNac Transferase 3/GALNT3 Antibody [H00002591-B01P] - Analysis of GALNT3 expression in transfected 293T cell line by GALNT3 polyclonal antibody. Lane 1: GALNT3 transfected lysate(15.51 KDa). Lane 2: Non-transfected lysate.

Polypeptide GalNac Transferase 3/GALNT3 Antibody - H00002591-D01P from Novus Biologicals

Host Rabbit
Clonality Polyclonal
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