Grm2

Gene Symbol Grm2
Entrez Gene 108068
Alt Symbol 4930441L02Rik, Gprc1b, mGluR2, mGluR7
Species Mouse
Gene Type protein-coding
Description glutamate receptor, metabotropic 2
Other Description G protein coupled receptor, family C, group 1, member B|G protein-coupled receptor, family C, group 1, member B|metabotropic glutamate receptor 2
Swissprots Q14BI2
Accessions EDL21160 Q14BI2 AK015353 AK034263 AK046803 AY255603 AAO85115 BC115866 AAI15867 BQ174642 BY290719 CK619406 NM_001160353 NP_001153825
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. {ECO:0000269|PubMed:18297054, ECO:0000269|PubMed:23129762}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite.
Tissue Specificity Detected in neurons in brain cortex (at protein level). {ECO:0000269|PubMed:18297054, ECO:0000269|PubMed:23129762}.
Top Pathways Glutamatergic synapse, Cocaine addiction, Neuroactive ligand-receptor interaction

mGluR2 Antibody - 12056 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with constructs expressing HA-tagged full-length mouse mGluR2 (mGluR2-HA; +) or HA-tagged full-length mouse mGluR3 (mGluR3-HA; +), using mGluR2 Antibody (upper) or HA-Tag (C29F4) Rabbit mAb #3724 (lower). HA-tagged mGluR cDNAs were a gift from Dr. Gonzalez-Maeso (Mount Sinai School of Medicine, NY).

Anti-Metabotropic Glutamate Receptor 2+3 antibody - ab6438 from Abcam

Prices $394.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab6438 staining the Metabotropic Glutamate Receptor 2+3 in Chicken brain tissue sections by IHC-Fr (Frozen sections). Tissue samples were fixed with paraformaldehyde and blocked with 5% serum for 1 hour 30 minutes at 20°C. The sample was incubated with primary antibody (1/100) at 4°C for 8 hours. Ab6720 (1/400) was used as secondary antibody. See Abreview

Anti-Metabotropic Glutamate Receptor 2 antibody [mG2Na-s] - ab15672 from Abcam

Prices $385.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone mG2Na-s
Anti-Metabotropic Glutamate Receptor 2 antibody [mG2Na-s] (ab15672) at 1 µg/ml + Brain (Rat) Tissue Lysate at 10 µgSecondaryGoat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

mGluR2/3 Antibody - NBP2-21064 from Novus Biologicals

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: metabotropic Glutamate Receptor 2/3 Antibody [NBP2-21064] - Rat brain shows bands migrating at Mr=100,000 and 190,000 which may be a dimer of the smaller band.

Anti-Glutamate Receptor 2/3, Metabotropic (mGluR2/3) antibody produced in rabbit - G9790 from Sigma-Aldrich

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GRM2 antibody - 70R-30965 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GRM2 antibody - STJ72309 from St John's Laboratory Ltd

Host Goat
Clonality Polyclonal

mGluR2/3 - RA13102 from Neuromics

Prices $95.00, $325.00
Sizes 20 µg blocking peptide, 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM2 monoclonal antibody, clone nH3Ob-t - DCABH-4707 from Creative Diagnostics

Host Mouse
Clonality Monoclonal
Clone nH3Ob-t

mGluR2 - 191 103 from Synaptic Systems

Host Rabbit
Clonality Polyclonal
Cat. No. 191 002 antibody dilution: 1 : 1000 sample: rat brain homogenate

GRM2, Polyclonal Antibody - MBS2516562 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

mGLUR2 antibody - 70R-49823 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-mGluR2/3 Antibody - 06-676 from Sigma-Aldrich

Prices $359.00
Sizes 06-676
Clonality Polyclonal
WB: Rat brain microsome extract probed with anti-mGluR2/3 at 0.5μg/ml

mGluR2 / GRM2 antibody - TA309171 from Acris Antibodies

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of 10 ug of rat hippocampal lysate showing the specific immunolabeling of the ~110k monomer and the ~220k dimer of mGluR2 and mGluR3.

Anti-mGluR2 Antibody - 07-261-I from EMD Millipore

Host Rabbit
Clonality Polyclonal

mGluR2/3 - 61-177 from Antibodies Incorporated

Prices $358.00
Sizes sent in liquid form in tris glycine with 0.1% sodium azide and 1% bsa, ph 7.8
Host Rabbit
Clonality Polyclonal
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