NR2E1

Gene Symbol NR2E1
Entrez Gene 7101
Alt Symbol TLL, TLX, XTLL
Species Human
Gene Type protein-coding
Description nuclear receptor subfamily 2, group E, member 1
Other Description nuclear receptor TLX|nuclear receptor subfamily 2 group E member 1|protein tailless homolog|tailes-related receptor|tailless homolog
Swissprots Q9Y466 Q6ZMP8
Accessions EAW48385 EAW48386 Q9Y466 AB307709 BAH02300 AF220532 AAG31945 AF411525 AAL05871 AK131541 BAD18677 BC028031 AAH28031 DA806924 HQ692846 ADZ17357 Y13276 CAA73725 XM_011536094 XP_011534396 NM_001286102 NP_001273031 NM_003269 NP_003260
Function Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half- site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acic receptor (RAR) regulation in retinal cells. {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}.
Tissue Specificity Brain specific. Present in all brain sections tested, highest levels in the caudate nucleus and hippocampus, weakest levels in the thalamus. {ECO:0000269|PubMed:9628820}.

NR2E1 (B-10) - sc-377240 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NR2E1 (B-10): sc-377240. Western blot analysis of NR2E1 expression in Jurkat (A) and SH-SY5Y (B) whole cell lysates.

NR2E1 (N-16) - sc-79573 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NR2E1 (H-102) - sc-292096 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NR2E1 (H-102): sc-292096. Western blot analysis of NR2E1 expression in Jurkat (A) and NIH/3T3 (B) nuclear extracts.

NR2E1 (EE-9) - sc-100905 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
NR2E1 (EE-9): sc-100905. Western blot analysis of NR2E1 expression in NIH/3T3 whole cell lysate.

NR2E1 (S-23) - sc-133843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
NR2E1 (S-23): sc-133843. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human skin tissue showing nuclear and cytoplasmic localization.

Anti-NR2E1 / Tailless antibody [EPR4491] - ab109179 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4491
All lanes : Anti-NR2E1 / Tailless antibody [EPR4491] (ab109179) at 1/1000 dilutionLane 1 : Fetal brain lysateLane 2 : Human hippocampus lysateLane 3 : SH-SY5Y lysateLane 4 : Jurkat lysateLysates/proteins at 10 µg per lane.

Anti-NR2E1 / TLX Antibody - LS-C126069 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-NR2E1 / TLX Antibody (aa75-102, APC) - LS-C264718 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NR2E1 / TLX Antibody (aa75-102, AP) - LS-C264719 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NR2E1 / TLX Antibody (aa75-102, Biotin) - LS-C264720 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NR2E1 / TLX Antibody (aa75-102, FITC) - LS-C264721 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NR2E1 / TLX Antibody (aa75-102, Azide-free, HRP) - LS-C264722 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NR2E1 / TLX Antibody (aa75-102, PE) - LS-C264723 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NR2E1 / TLX Antibody (aa75-102) - LS-C329909 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NR2E1 / TLX Antibody (clone 1C4) - LS-C198347 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C4
NR2E1 monoclonal antibody (M01), clone 1C4 Western Blot analysis of NR2E1 expression in NIH/3T3.

Anti-NR2E1 / TLX Antibody (Internal, clone EPR4491) - LS-C138586 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4491
Western blot analysis on (A) fetal brain, (B) human hippocampus, (C) SH-SY5Y, and (D) Jurkat lysates using anti-NR2E1 antibody.

Anti-NR2E1 / TLX Antibody (aa283-332) - LS-C201494 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human THP-1. NR2E1 antibody dilution 1.0 ug/ml.

Anti-NR2E1 / TLX Antibody (aa75-102) - LS-C158001 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NR2E1 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NR2E1 antibody detected the NR2E1 protein (arrow).

Anti-NR2E1 / TLX Antibody (N-Terminus) IHC-plus™ - LS-B4564 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NR2E1 antibody IHC of human colon, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4564 concentration 5 ug/ml.

Anti-NR2E1 / TLX Antibody (aa144-193) IHC-plus™ - LS-B11934 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Testis: Formalin-fixed, paraffin embedded (FFPE) tissue.

Anti-NR2E1 / TLX Antibody (N-Terminus) IHC-plus™ - LS-A2516 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NR2E1 antibody LS-A2516 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-NR2E1 / TLX Antibody (aa95-144) IHC-plus™ - LS-B3505 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NR2E1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3505 concentration 5 ug/ml.

TLX/NR2E1 Antibody (H6506) - PP-H6506-00 from Novus Biologicals

Prices $393.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone H6506

TLX/NR2E1 Antibody (4D2) - H00007101-M06 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4D2
Western Blot: TLX/NR2E1 Antibody (4D2) [H00007101-M06] - Western Blot analysis of NR2E1 expression in NIH/3T3 ( Cat # L018V1 ).

TLX/NR2E1 Antibody (4G12) - H00007101-M03A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 4G12
Western Blot: NR2E1/Tailless Antibody (4G12) [H00007101-M03A] - NR2E1 monoclonal antibody (M03), clone 4G12. Western Blot analysis of NR2E1 expression in NIH/3T3.
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