NR2E1

Gene Symbol NR2E1
Entrez Gene 7101
Alt Symbol TLL, TLX, XTLL
Species Human
Gene Type protein-coding
Description nuclear receptor subfamily 2, group E, member 1
Other Description nuclear receptor TLX|nuclear receptor subfamily 2 group E member 1|protein tailless homolog|tailes-related receptor|tailless homolog
Swissprots Q9Y466 Q6ZMP8
Accessions EAW48385 EAW48386 Q9Y466 AB307709 BAH02300 AF220532 AAG31945 AF411525 AAL05871 AK131541 BAD18677 BC028031 AAH28031 DA806924 HQ692846 ADZ17357 Y13276 CAA73725 XM_011536094 XP_011534396 NM_001286102 NP_001273031 NM_003269 NP_003260
Function Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half- site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acic receptor (RAR) regulation in retinal cells. {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}.
Tissue Specificity Brain specific. Present in all brain sections tested, highest levels in the caudate nucleus and hippocampus, weakest levels in the thalamus. {ECO:0000269|PubMed:9628820}.

NR2E1 CRISPR/Cas9 KO Plasmid (h) - sc-403493 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E1 HDR Plasmid (h) - sc-403493-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E1 Double Nickase Plasmid (h) - sc-403493-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E1 Double Nickase Plasmid (h2) - sc-403493-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E1 CRISPR Activation Plasmid (h) - sc-403493-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E1 CRISPR Activation Plasmid (h2) - sc-403493-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E1 Lentiviral Activation Particles (h) - sc-403493-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E1 Lentiviral Activation Particles (h2) - sc-403493-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E1 siRNA (h) - sc-75954 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NR2E1 shRNA Plasmid (h) - sc-75954-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NR2E1 shRNA (h) Lentiviral Particles - sc-75954-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TLX/NR2E1 RNAi - H00007101-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU130251 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN2146 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2146 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09267 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09267

NR2E1 siRNA (Human) - CRH4868 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NR2E1 CRISPR/Cas9 KO Plasmid (h2) - sc-403493-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NR2E1 HDR Plasmid (h2) - sc-403493-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human NR2E1 (NM_003269.3) - SHH354756 from Creative biogene

Category siRNA
Species Reactivities Human

Human NR2E1 siRNA - orb265370 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NR2E1 shRNA Plasmid (Human) - CHH4868 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NR2E1 miRNA 3'UTR clone - MiUTR3H-06313 from Creative biogene

Species Reactivities Human
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