Ccl12

Gene Symbol Ccl12
Entrez Gene 20293
Alt Symbol MCP-5, Scya12
Species Mouse
Gene Type protein-coding
Description chemokine (C-C motif) ligand 12
Other Description C-C motif chemokine 12|MCP-1-related chemokine|monocyte chemoattractant protein 5|monocyte chemotactic protein 5|small inducible cytokine A12|small-inducible cytokine A12
Swissprots Q9QYD6 Q62401
Accessions EDL01207 EDL01219 Q62401 AF065934 AAF15384 AF065935 AAF15385 AF065936 AAF15386 AF065937 AAF15387 AF065938 AAF15388 AK012356 BAB28185 BC027520 AAH27520 U50712 AAB50053 U66670 AAB49424 NM_011331 NP_035461
Function Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
Subcellular Location Secreted.
Tissue Specificity Predominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon.
Top Pathways Chagas disease (American trypanosomiasis), Malaria, Chemokine signaling pathway, Rheumatoid arthritis, NOD-like receptor signaling pathway

MCP-5 (G-12) - sc-33226 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MCP-5 (K-19) - sc-9718 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MCP-5 (K-19): sc-9718. Western blot analysis of mouse recombinant MCP-5.

MCP-5 (K-12) - sc-33228 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MCP-5 (V-20) - sc-9720 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MCP-5 (V-20): sc-9720. Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate tissue showing cytoplasmic and membrane staining of glandular cells.

Anti-MCP5 antibody - ab9737 from Abcam

Prices $450.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MCP5 antibody (Biotin) - ab84272 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CCL12 / MCP5 Antibody (Biotin) - LS-C318798 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CCL12 / MCP5 Antibody (aa28-104) - LS-C295408 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of recombinant CCL12 / MCP5.

Anti-CCL12 / MCP5 Antibody (Biotin) - LS-C104806 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Sandwich ELISA of MCP5 / CCL12 antibody LS-C104806

Anti-CCL12 / MCP5 Antibody - LS-C104804 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western Blot (non-reducing) of MCP5 / CCL12 antibody LS-C104804

Anti-CCL12 / MCP5 Antibody - LS-C144001 from LifeSpan Bioscience

Host Rat
Clonality Monoclonal

Anti-CCL12 / MCP5 Antibody - LS-C285683 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CCL12 / MCP5 Antibody (aa28-104, FITC) - LS-C304052 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CCL12 / MCP5 Antibody (aa28-104, Biotin) - LS-C301266 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CCL12 / MCP5 Antibody (FITC) - LS-C317041 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CCL12 / MCP5 Antibody (HRP) - LS-C317042 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

CCL12/MCP-5 Antibody - AF428 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Recombinant Mouse CCL12/MCP‑5 (Catalog # 428-P5) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CCR2A in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Mouse CCL12/MCP‑5 (0.2 µg/mL) is neutralized (green line) by increasing concentrations of Mouse CCL12/MCP‑5 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF428). The ND50 is typically 0.8-4.0 µg/mL.

CCL12/MCP-5 Antibody (63205) [Unconjugated] - MAB428 from Novus Biologicals

Prices $99.00, $269.00, $699.00
Sizes 25 µg, 100 µg, 500 µg
Host Rat
Clonality Monoclonal
Clone 63205
Recombinant Mouse CCL12/MCP‑5 (Catalog # 428‑P5) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CCR2A in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Mouse CCL12/MCP‑5 (10 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse CCL12/MCP‑5 Monoclonal Antibody (Catalog # MAB428). The ND50 is typically 0.5‑2.5 µg/mL. Maximum neutralization observed was around 80%.

CCL12/MCP-5 Antibody (147801) [Unconjugated] - MAB4281 from Novus Biologicals

Prices $99.00, $269.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 147801
Recombinant Mouse CCL12/MCP‑5 (Catalog # 428‑P5) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CCR2A in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Mouse CCL12/MCP‑5 (0.2 µg/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse CCL12/MCP‑5 Monoclonal Antibody (Catalog # MAB4281). The ND50 is typically 0.5-2.5 µg/mL.

CCL12/MCP-5 Antibody (RM0169-8J25) - NBP2-12089 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone RM0169-8J25

CCL12/MCP-5 Antibody [Biotin] - BAF428 from Novus Biologicals

Prices $420.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

CCL-12 antibody [8J25] - GTX53260 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rat
Clonality Monoclonal
Clone 8J25

Mouse CCL12/MCP-5 MAb (Clone 63205), Rat IgG2A - MAB428-100 from R&D Systems

Host Rat
Clonality Monoclonal
Clone 63205
Chemotaxis Induced by CCL12/MCP‑5 and Neutral­ization by Mouse CCL12/MCP‑5 Antibody.Recombinant Mouse CCL12/MCP‑5 (Catalog # 428‑P5) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CCR2A in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Mouse CCL12/MCP‑5 (10 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse CCL12/MCP‑5 Monoclonal Antibody (Catalog # MAB428). The ND50 is typically 0.5‑2.5 µg/mL. Maximum neutralization observed was around 80%.

Mouse CCL12/MCP-5 MAb (Clone 63205), Rat IgG2A - MAB428-500 from R&D Systems

Host Rat
Clonality Monoclonal
Clone 63205
Chemotaxis Induced by CCL12/MCP‑5 and Neutral­ization by Mouse CCL12/MCP‑5 Antibody.Recombinant Mouse CCL12/MCP‑5 (Catalog # 428‑P5) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CCR2A in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Mouse CCL12/MCP‑5 (10 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse CCL12/MCP‑5 Monoclonal Antibody (Catalog # MAB428). The ND50 is typically 0.5‑2.5 µg/mL. Maximum neutralization observed was around 80%.

Mouse CCL12/MCP-5 MAb (Clone 63205), Rat IgG2A - MAB428-SP from R&D Systems

Host Rat
Clonality Monoclonal
Clone 63205
Chemotaxis Induced by CCL12/MCP‑5 and Neutral­ization by Mouse CCL12/MCP‑5 Antibody.Recombinant Mouse CCL12/MCP‑5 (Catalog # 428‑P5) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CCR2A in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Mouse CCL12/MCP‑5 (10 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse CCL12/MCP‑5 Monoclonal Antibody (Catalog # MAB428). The ND50 is typically 0.5‑2.5 µg/mL. Maximum neutralization observed was around 80%.
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