SPHK2

Gene Symbol	SPHK2
Entrez Gene	56848
Alt Symbol	SK 2, SK-2, SPK 2, SPK-2
Species	Human
Gene Type	protein-coding
Description	sphingosine kinase 2
Other Description	sphingosine kinase type 2
Swissprots	Q9BRN1 Q9NRA0 B4DU87 A0T4C8 Q9NWU7 Q9H0Q2
Accessions	CBH26133 CBX51413 EAW52365 EAW52366 EAW52367 EAW52368 EAW52369 EAW52370 EAW52371 Q9NRA0 AB100373 BAC55583 AF245447 AAF74124 AK000599 BAA91280 AK074601 BAC11085 AK122735 BAG53695 AK125560 AK297787 BAH12667 AK300541 BAG62249 AL136701 CAB66636 BC006161 AAH06161 BC010671 AAH10671 BI224962 DA926908 DB053266 DB367710 DQ896790 ABM87789 EF107108 ABK81123 EU176470 ABW03921 XM_006723291 XP_006723354 XM_006723292 XP_006723355 XM_011527133 XP_011525435 XM_011527134 XP_011525436 XM_011527135 XP_011525437 NM_001204158 NP_001191087 NM_001204159 NP_001191088 NM_001204160 NP_001191089 NM_001243876 NP_001230805 NM_020126 NP_064511
Function	Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro- dihydrosphingosine, D-erythro-sphingosine and L-threo- dihydrosphingosine. Binds phosphoinositides. {ECO:0000269|PubMed:19168031}.
Subcellular Location	Isoform 1: Cytoplasm. Membrane.
Top Pathways	VEGF signaling pathway, Calcium signaling pathway, Fc gamma R-mediated phagocytosis, Tuberculosis, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human SPHK2 full length protein - ab125634 from Abcam Category Protein Prices $239.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Active human SPHK2 full length protein - ab42625 from Abcam Category Protein Prices $532.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Human SPHK2 full length protein - ab163404 from Abcam Category Protein Source Wheat germ Species Human

Human SPHK2 protein fragment - ab163405 from Abcam Category Protein Source Wheat germ Species Human

Mouse SPHK2 full length protein - ab61643 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Mouse

SPHK2 Antibody Blocking Peptide - LS-E8790 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPHK2 Blocking Peptide - LS-E8789 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Sphingosine Kinase 2/SPHK2 Protein - H00056848-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Sphingosine Kinase 2/SPHK2 Recombinant Protein - H00056848-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Sphingosine Kinase 2/SPHK2 Peptide - P2412 from Novus Biologicals Category Peptide Species Human

Sphingosine Kinase 2/SPHK2 Peptide - P2411 from Novus Biologicals Category Peptide Species Human

SPHK2-Antibody-C-term-Blocking-Peptide - BP7238b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPHK2-Antibody-N-term-Blocking-Peptide - BP7238a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Sphingosine Kinase 2/SPHK2, CF - 5298-SK-010 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Asn2-Pro654, with an N-terminal 5-His tag

Sphingosine Kinase 2 enzyme - orb108373 from Biorbyt Category Protein Prices $553.00 Sizes 10 μg Species Human

Sphingosine Kinase 2 peptide - orb108401 from Biorbyt Category Peptide Prices $374.00 Sizes 50 μg

SPK2 Blocking Peptide - 33R-10973 from Fitzgerald Category Peptide Prices $115.00 Sizes 50 µg

Sphingosine kinase 2 / SPK2 (His-tagged), Active Enzyme - AR00178PU-N from Acris Antibodies Category Protein Prices $480.00 Sizes 10 µg Source SF9 cells Species Human

Sphingosine kinase 2 / SPK2 (Long Form, Active Enzyme, His-tagged) - AR00186PU-N from Acris Antibodies Category Protein Prices $480.00 Sizes 10 µg Source SF9 cells Species Human

Sphingosine kinase 2 / SPK2 - H00056848-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Sphingosine kinase 2 / SPK2 - H00056848-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Sphingosine kinase 2 / SPK2 - H00056848-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Sphingosine kinase 2 / SPK2 - H00056848-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Sphingosine kinase 2 / SPK2 control peptide - AP05167CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

Sphingosine kinase 2 / SPK2 control peptide - AP05265CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

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