| Gene Symbol |
VPS33B
|
| Entrez Gene |
26276
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vacuolar protein sorting 33 homolog B (yeast)
|
| Other Description |
vacuolar protein sorting-associated protein 33B
|
| Swissprots |
Q96K14 Q9H267 Q9NSF3 Q9NRP6 B3KQF6
|
| Accessions |
CAF86824 EAX02139 EAX02140 Q9H267 AF201694 AAF91174 AF308803 AAG34680 AJ713428 AK027754 BAB55345 AK074863 BAG52018 AK293688 BAH11570 AK300608 BAH13313 AK308480 AK315721 AL357472 CAB93109 BC016445 AAH16445 CB048637 DA020491 DC397488 XM_005254884 XP_005254941 XM_005254887 XP_005254944 XM_005254888 XP_005254945 XM_011521448 XP_011519750 XM_011521449 XP_011519751 NM_001289148 NP_001276077 NM_001289149 NP_001276078 NM_018668 NP_061138
|
| Function |
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages. {ECO:0000269|PubMed:18474358}.
|
| Subcellular Location |
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes. Colocalizes with M.tuberculosis PtpA in the cytosol of tuberculosis-infected macrophages and associates with phagosomes. Colocalizes in clusters with VIPAS39 at cytoplasmic organelles.
|
| Tissue Specificity |
Ubiquitous; highly expressed in testis and low expression in the lung.
|
![Western Blot: VPS33B Overexpression Lysate (Adult Normal) [NBL1-17745] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VPS33B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9977_VPS33B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17745-img0002.jpg)