| Gene Symbol |
SERINC5
|
| Entrez Gene |
256987
|
| Alt Symbol |
C5orf12, TPO1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serine incorporator 5
|
| Other Description |
-
|
| Swissprots |
Q495A6 B4DMH7 Q86VE9 Q495A4
|
| Accessions |
EAW95843 EAW95844 EAW95845 Q86VE9 AF498273 AAP06800 AK026295 AK297467 BAG59889 BC101280 AAI01281 BC101281 AAI01282 BC101282 BC101283 AAI01284 BU681476 CR936687 DC354040 XM_011543304 XP_011541606 NM_001174071 NP_001167542 NM_001174072 NP_001167543 NM_178276 NP_840060 NR_126060 NR_126061
|
| Function |
Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in placenta, skeletal muscle, spleen, thymus, testis and peripheral leukocyte and is expressed weakly in the heart, liver and fetal brain. {ECO:0000269|PubMed:12688535}.
|
![Western Blot: SERINC5 Overexpression Lysate (Adult Normal) [NBP2-10254] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SERINC5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1243_SERINC5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10254-img0001.jpg)