Gene Symbol | SERINC5 |
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Entrez Gene | 256987 |
Alt Symbol | C5orf12, TPO1 |
Species | Human |
Gene Type | protein-coding |
Description | serine incorporator 5 |
Other Description | - |
Swissprots | Q495A6 B4DMH7 Q86VE9 Q495A4 |
Accessions | EAW95843 EAW95844 EAW95845 Q86VE9 AF498273 AAP06800 AK026295 AK297467 BAG59889 BC101280 AAI01281 BC101281 AAI01282 BC101282 BC101283 AAI01284 BU681476 CR936687 DC354040 XM_011543304 XP_011541606 NM_001174071 NP_001167542 NM_001174072 NP_001167543 NM_178276 NP_840060 NR_126060 NR_126061 |
Function | Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Highly expressed in placenta, skeletal muscle, spleen, thymus, testis and peripheral leukocyte and is expressed weakly in the heart, liver and fetal brain. {ECO:0000269|PubMed:12688535}. |
SERINC5 CRISPR/Cas9 KO Plasmid (h) - sc-418168 from Santa Cruz Biotechnology
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SERINC5 HDR Plasmid (h) - sc-418168-HDR from Santa Cruz Biotechnology
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SERINC5 Double Nickase Plasmid (h) - sc-418168-NIC from Santa Cruz Biotechnology
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SERINC5 Double Nickase Plasmid (h2) - sc-418168-NIC-2 from Santa Cruz Biotechnology
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SERINC5 CRISPR Activation Plasmid (h) - sc-418168-ACT from Santa Cruz Biotechnology
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SERINC5 CRISPR Activation Plasmid (h2) - sc-418168-ACT-2 from Santa Cruz Biotechnology
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SERINC5 Lentiviral Activation Particles (h) - sc-418168-LAC from Santa Cruz Biotechnology
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SERINC5 Lentiviral Activation Particles (h2) - sc-418168-LAC-2 from Santa Cruz Biotechnology
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SERINC5 siRNA (h) - sc-91978 from Santa Cruz Biotechnology
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SERINC5 shRNA Plasmid (h) - sc-91978-SH from Santa Cruz Biotechnology
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SERINC5 shRNA (h) Lentiviral Particles - sc-91978-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU143031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19126 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19126 from Sigma-Aldrich
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SERINC5 siRNA (Human) - CRJ6774 from Cohesion Biosciences
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SERINC5 - MBS8237037 from MyBioSource
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shRNA set against Human SERINC5 (NM_178276.5) - SHH404844 from Creative biogene
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SERINC5 shRNA Plasmid (Human) - CHJ6774 from Cohesion Biosciences
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SERINC5 miRNA 3'UTR clone - MiUTR3H-13301 from Creative biogene
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