Gene Symbol |
SERINC5
|
Entrez Gene |
256987
|
Alt Symbol |
C5orf12, TPO1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
serine incorporator 5
|
Other Description |
-
|
Swissprots |
Q495A6 B4DMH7 Q86VE9 Q495A4
|
Accessions |
EAW95843 EAW95844 EAW95845 Q86VE9 AF498273 AAP06800 AK026295 AK297467 BAG59889 BC101280 AAI01281 BC101281 AAI01282 BC101282 BC101283 AAI01284 BU681476 CR936687 DC354040 XM_011543304 XP_011541606 NM_001174071 NP_001167542 NM_001174072 NP_001167543 NM_178276 NP_840060 NR_126060 NR_126061
|
Function |
Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity). {ECO:0000250}.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Tissue Specificity |
Highly expressed in placenta, skeletal muscle, spleen, thymus, testis and peripheral leukocyte and is expressed weakly in the heart, liver and fetal brain. {ECO:0000269|PubMed:12688535}.
|