Gene Symbol | Dnmt3l |
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Entrez Gene | 54427 |
Alt Symbol | D6Ertd14e, ecat7 |
Species | Mouse |
Gene Type | protein-coding |
Description | DNA (cytosine-5-)-methyltransferase 3-like |
Other Description | DNA (cytosine-5)-methyltransferase 3-like |
Swissprots | Q9CWR8 |
Accessions | EDL31748 EDL31749 Q9CWR8 AF220524 AAF73868 AJ404467 CAB94726 AK010434 BAB26936 AV473569 AV511576 BC083147 AAH83147 EF051621 EF051622 EF051623 EF051624 ABN46989 XM_011243514 XP_011241816 NM_001081695 NP_001075164 NM_001284197 NP_001271126 NM_001284198 NP_001271127 NM_001284199 NP_001271128 NM_001284200 NP_001271129 NM_019448 NP_062321 |
Function | Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. {ECO:0000269|PubMed:11719692, ECO:0000269|PubMed:15671018}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed in testis, thymus, ovary, and heart. |
DNMT3L Antibody (Mouse Specific) - 12309 from Cell Signaling Technology
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DNMT3L (E1Y7Q) Rabbit mAb (Mouse Specific) - 13451 from Cell Signaling Technology
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Dnmt3L (S-14) - sc-103480 from Santa Cruz Biotechnology
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ANTI-MOUSE DNMT3L antibody produced in rabbit - SAB1302436 from Sigma-Aldrich
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Anti-Mouse Dnmt3l antibody produced in rabbit - SAB1300031 from Sigma-Aldrich
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Mouse-Dnmt3L-Antibody - AP1062a from Abgent, a WuXi AppTec company
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Mouse-Dnmt3l-Antibody-Center - AP21127a from Abgent, a WuXi AppTec company
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Dnmt3L Antibody (OAAB07283) - OAAB07283 from Aviva Systems Biology
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DNMT3L antibody - AP11074PU-N from Acris Antibodies
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DNMT3L antibody - PAB2230 from Acris Antibodies
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Rabbit Anti-Mouse Dnmt3L - 102-10722 from RayBiotech
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Dnmt3L antibody - STJ40956 from St John's Laboratory Ltd
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Anti-DNMT3L (aa 392-421) polyclonal antibody - DPABH-28603 from Creative Diagnostics
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Dnmt3l Antibody - middle region (OAAB19087) - OAAB19087 from Aviva Systems Biology
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DNMT3L Antibody (OARA02467) - OARA02467 from Aviva Systems Biology
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Mouse-Dnmt3l-Antibody-C-term - AP21520b from Abgent, a WuXi AppTec company
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Dnmt3l, Polyclonal Antibody - MBS9215259 from MyBioSource
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Dnmt3L, Polyclonal Antibody - MBS9207537 from MyBioSource
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Dnmt3l , Polyclonal Antibody - MBS9215836 from MyBioSource
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Mouse Dnmt3L Antibody - 55-295 from ProSci
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DNMT3L Antibody - C-terminal region (OAAB21456) - OAAB21456 from Aviva Systems Biology
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