Gene Symbol | HS3ST2 |
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Entrez Gene | 9956 |
Alt Symbol | 30ST2, 3OST2 |
Species | Human |
Gene Type | protein-coding |
Description | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
Other Description | 3-OST-2|h3-OST-2|heparan sulfate 3-O-sulfotransferase 2|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2|heparan sulfate glucosamine 3-O-sulfotransferase 2|heparin-glucosamine 3-O-sulfotransferase |
Swissprots | Q52LZ1 Q9Y278 |
Accessions | EAW55840 Q9Y278 AB209794 BAD93031 AF105374 AAD30206 AF105375 AAD30207 AK313463 BAG36249 AY359095 AAQ89453 BC093734 AAH93734 BC093736 AAH93736 XM_011546001 XP_011544303 XM_011546002 XP_011544304 NM_006043 NP_006034 |
Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in GlcA2S-GlcNS. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in the brain and weakly expressed in the heart, placenta, lung and skeletal muscle. {ECO:0000269|PubMed:9988767}. |
Top Pathways | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
HS3ST2 (G-6) - sc-514361 from Santa Cruz Biotechnology
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HS3ST2 (P-12) - sc-107227 from Santa Cruz Biotechnology
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HS3ST2 (T-15) - sc-107228 from Santa Cruz Biotechnology
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Anti-HS3ST2 antibody - ab56896 from Abcam
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Anti-HS3ST2 Antibody (aa317-346, AP) - LS-C258901 from LifeSpan Bioscience
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Anti-HS3ST2 Antibody (aa317-346, Biotin) - LS-C258904 from LifeSpan Bioscience
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Anti-HS3ST2 Antibody (aa317-346, APC) - LS-C258902 from LifeSpan Bioscience
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Anti-HS3ST2 Antibody (aa317-346, Azide-free, HRP) - LS-C258906 from LifeSpan Bioscience
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Anti-HS3ST2 Antibody (aa317-346, FITC) - LS-C258905 from LifeSpan Bioscience
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Anti-HS3ST2 Antibody (aa268-367) - LS-C308316 from LifeSpan Bioscience
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Anti-HS3ST2 Antibody (aa317-346, PE) - LS-C258907 from LifeSpan Bioscience
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Anti-HS3ST2 Antibody (aa324-354) - LS-C322095 from LifeSpan Bioscience
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Anti-HS3ST2 Antibody (aa317-346) - LS-C165025 from LifeSpan Bioscience
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HS3ST2 Antibody - NBP1-89374 from Novus Biologicals
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HS3ST2 Antibody - NBP2-16880 from Novus Biologicals
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Anti-HS3ST2 antibody produced in rabbit - HPA017736 from Sigma-Aldrich
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Anti-HS3ST2 antibody produced in rabbit - SAB2701346 from Sigma-Aldrich
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Monoclonal Anti-HS3ST2 antibody produced in mouse - WH0009956M1 from Sigma-Aldrich
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HS3ST2-Antibody-C-term - AP9513b from Abgent, a WuXi AppTec company
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HS3ST2 Antibody - C-terminal region (OAAB06110) - OAAB06110 from Aviva Systems Biology
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HS3ST2 antibody - GTX118041 from GeneTex
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Anti -HS3ST2 (Heparan Sulfate Glucosamine 3-O-sulfotransferase 2, Heparan SulfateD-glucosaminyl 3-O-sulfotransferase 2, 3-OST-2, Heparan Sulfate 3-O-sulfotransferase 2,h3-OST-2, 3OST2, UNQ2442/PRO5004) - 128073 from USBiological Life Science
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Anti -HS3ST2 (Heparan Sulfate Glucosamine 3-O-sulfotransferase 2, Heparan SulfateD-glucosaminyl 3-O-sulfotransferase 2, 3-OST-2, Heparan Sulfate 3-O-sulfotransferase 2,h3-OST-2, 3OST2, UNQ2442/PRO5004) (AP) - 128073-AP from USBiological Life Science
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Anti -HS3ST2 (Heparan Sulfate Glucosamine 3-O-sulfotransferase 2, Heparan SulfateD-glucosaminyl 3-O-sulfotransferase 2, 3-OST-2, Heparan Sulfate 3-O-sulfotransferase 2,h3-OST-2, 3OST2, UNQ2442/PRO5004) (Biotin) - 128073-Biotin from USBiological Life Science
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Anti -HS3ST2 (Heparan Sulfate Glucosamine 3-O-sulfotransferase 2, Heparan SulfateD-glucosaminyl 3-O-sulfotransferase 2, 3-OST-2, Heparan Sulfate 3-O-sulfotransferase 2,h3-OST-2, 3OST2, UNQ2442/PRO5004) (FITC) - 128073-FITC from USBiological Life Science
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