CMPK1

Gene Symbol	CMPK1
Entrez Gene	51727
Alt Symbol	CK, CMK, CMPK, UMK, UMP-CMPK, UMPK
Species	Human
Gene Type	protein-coding
Description	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
Other Description	CK\|UMP-CMP kinase\|UMP/CMP kinase\|cytidylate kinase\|dCMP kinase\|deoxycytidylate kinase\|nucleoside-diphosphate kinase\|uridine monophosphate kinase\|uridine monophosphate/cytidine monophosphate kinase
Swissprots	B4DPU7 Q5SVZ0 E9PGI8 Q9UIA2 Q53GB7 P30085 Q9UBQ8 Q96C07
Accessions	EAX06869 EAX06870 EAX06871 P30085 AF070416 AAF17709 AF087865 AAP97174 AF110643 AAD48583 AF112216 AAF17204 AF259961 AAG22609 AK025258 AK027204 AK223014 BAD96734 AK293238 BAG56775 AK294294 BAG57577 AK298502 BAG60709 AK312693 BAG35572 BC014961 AAH14961 BC017806 DB494965 DQ892213 ABM83139 DQ895408 ABM86334 DQ895409 ABM86335 NM_001136140 NP_001129612 NM_016308 NP_057392 NR_046394 NR_046395
Function	Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. {ECO:0000255\|HAMAP-Rule:MF_03172, ECO:0000269\|PubMed:10462544, ECO:0000269\|PubMed:11912132, ECO:0000269\|PubMed:23416111}.
Subcellular Location	Nucleus. Cytoplasm. Note=Predominantly nuclear.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269\|PubMed:11681623}.
Top Pathways	Pyrimidine metabolism

CMPK (H-2) - sc-376153 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

CMPK (H-2): sc-376153. Western blot analysis of CMPK expression in non-transfected: sc-117752 (A) and human CMPK transfected: sc-170057 (B) 293T whole cell lysates.

CMPK (K-14) - sc-104147 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

CMPK (F-5) - sc-376209 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

CMPK (F-5): sc-376209. Western blot analysis of CMPK expression in non-transfected: sc-117752 (A) and human CMPK transfected: sc-170057 (B) 293T whole cell lysates.

CMPK (H-105) - sc-292300 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

CMPK (H-105): sc-292300. Western blot analysis of CMPK expression in K-562 (A) and Hep G2 (B) whole cell lysates.

CMPK (T-15) - sc-104149 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-UMP/CMP kinase antibody - ab169440 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-UMP/CMP kinase antibody (ab169440) at 1 µg/mlLane 1 : UMP/CMP kinase transfected lysateLane 2 : Non-transfected lysateLysates/proteins at 15 µl per lane.

Anti-UMP/CMP kinase antibody - ab77457 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-UMP/CMP kinase antibody (ab77457) at 1/500 dilution + K-562 cell lysate at 25 µgSecondarygoat anti-mouse IgG (H&L)- HRP conjugate at 1/2500 dilution

Anti-UMP/CMP kinase antibody - ab64934 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-UMP/CMP kinase antibody (ab64934) at 1/500 dilutionLane 1 : Extracts from HeLa cellsLane 2 : Extracts from HeLa cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-UMP/CMP kinase antibody [1D7] - ab124263 from Abcam

Prices	$464.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	1D7

Anti-UMP/CMP kinase antibody [1D7] (ab124263) + Extracts of K562 cell lysate

Anti-UMP/CMP kinase antibody [1H8] - ab139355 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1H8

All lanes : Anti-UMP/CMP kinase antibody [1H8] (ab139355) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY UMP/CMP kinase cDNALysates/proteins at 5 µg per lane.

Anti-CMPK / CMPK1 Antibody (clone 2B2) - LS-C174295 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2B2

IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-CMPK1 mouse monoclonal antibody.

Anti-CMPK / CMPK1 Antibody (clone 1H3) - LS-C337870 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1H3

Western blot of extracts (35ug) from 9 different cell lines by using anti-CMPK1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

Anti-CMPK / CMPK1 Antibody (clone 2A2) - LS-C174290 from LifeSpan Bioscience

Prices	$350.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2A2

IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CMPK1 mouse monoclonal antibody.

Anti-CMPK / CMPK1 Antibody (clone 1A9) - LS-C337883 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1A9

IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CMPK1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-CMPK / CMPK1 Antibody (clone 2F5) - LS-C174313 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2F5

IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-CMPK1 mouse monoclonal antibody.

Anti-CMPK / CMPK1 Antibody (clone 1H8) - LS-C174303 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1H8

Anti-CMPK / CMPK1 Antibody (clone 1A1) - LS-C174302 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1A1

Anti-CMPK / CMPK1 Antibody (aa1-50) - LS-C118852 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of extracts from HeLa cells, using KCY Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CMPK / CMPK1 Antibody (aa152-201) - LS-C151460 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

CMPK / CMPK1 antibody Western Blot of Mouse Heart.

Anti-CMPK / CMPK1 Antibody (C-Terminus) - LS-C101246 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-CMPK / CMPK1 Antibody (N-Terminus) - LS-C101245 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CMPK / CMPK1 Antibody (Glu36) - LS-C191962 from LifeSpan Bioscience

Prices	$345.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CMPK / CMPK1 Antibody - LS-C307004 from LifeSpan Bioscience

Prices	$455.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-CMPK / CMPK1 Antibody - LS-C309938 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CMPK / CMPK1 Antibody (aa61-110) - LS-C205834 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

CMPK / CMPK1 antibody Western Blot of Fetal Liver. Antibody dilution: 1 ug/ml.

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