Gene Symbol | G6PC2 |
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Entrez Gene | 57818 |
Alt Symbol | IGRP |
Species | Human |
Gene Type | protein-coding |
Description | glucose-6-phosphatase, catalytic, 2 |
Other Description | G-6-Pase 2|G6Pase 2|glucose-6-phosphatase 2|islet-specific G6CP-related protein|islet-specific glucose-6-phosphatase catalytic subunit-related protein|islet-specific glucose-6-phosphatase-related protein |
Swissprots | Q6AHZ0 Q9NQR9 E9PAX2 |
Accessions | AAF82810 AAY24099 EAX11291 Q9NQR9 AK310853 BC104778 AAI04779 BC113376 AAI13377 BQ268961 CA865646 CR627438 CAH10524 HQ258182 ADR82936 XM_011511564 XP_011509866 XM_011511565 XP_011509867 XM_011546941 XP_011545243 XM_011546942 XP_011545244 NM_001081686 NP_001075155 NM_021176 NP_066999 |
Function | May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15044018}; Multi-pass membrane protein {ECO:0000269|PubMed:15044018}. |
Tissue Specificity | Specifically expressed in pancreas and also detected to a lower extent in testis. Expressed by most islet cells in the pancreas (at protein level). {ECO:0000269|PubMed:11297555}. |
Top Pathways | Glucagon signaling pathway, AMPK signaling pathway, PI3K-Akt signaling pathway, Carbohydrate digestion and absorption, Glycolysis / Gluconeogenesis |
IGRP (C-19) - sc-33473 from Santa Cruz Biotechnology
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IGRP (G-16) - sc-33472 from Santa Cruz Biotechnology
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IGRP (H-60) - sc-66932 from Santa Cruz Biotechnology
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IGRP (N-20) - sc-33471 from Santa Cruz Biotechnology
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Glucose 6 phosphatase 2/IGRP Antibody - bs-13386R from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, ALEXA FLUOR® 350 Conjugated - bs-13386R-A350 from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, ALEXA FLUOR® 488 Conjugated - bs-13386R-A488 from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, ALEXA FLUOR® 555 Conjugated - bs-13386R-A555 from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, ALEXA FLUOR® 647 Conjugated - bs-13386R-A647 from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, Cy3 Conjugated - bs-13386R-Cy3 from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, Cy5 Conjugated - bs-13386R-Cy5 from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, Cy5.5 Conjugated - bs-13386R-Cy5.5 from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, Cy7 Conjugated - bs-13386R-Cy7 from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, FITC Conjugated - bs-13386R-FITC from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, Biotin Conjugated - bs-13386R-Biotin from Bioss
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Glucose 6 phosphatase 2/IGRP Antibody, HRP Conjugated - bs-13386R-HRP from Bioss
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Glucose-6-phosphatase 2 / G6PC2 (85-103) antibody - AP10077PU-N from Acris Antibodies
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Glucose-6-phosphatase 2 / G6PC2 antibody - H00057818-B01P from Acris Antibodies
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Glucose 6 phosphatase 2/IGRP Antibody, ALEXA FLUOR® 594 Conjugated - bs-13386R-A594 from Bioss
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G6PC2 Antibody,Biotin conjugated - CSB-PA873624LD01HU from Cusabio
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G6PC2 Antibody,FITC conjugated - CSB-PA873624LC01HU from Cusabio
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G6PC2 Antibody,HRP conjugated - CSB-PA873624LB01HU from Cusabio
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G6PC2 Antibody - CSB-PA873624LA01HU from Cusabio
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ANTI-G6PC2 (N-TERM) antibody produced in rabbit - SAB1301158 from Sigma-Aldrich
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Glucose 6 phosphatase 2/IGRP Antibody, ALEXA FLUOR® 680 Conjugated - bs-13386R-A680 from Bioss
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