G6PC2

Gene Symbol	G6PC2
Entrez Gene	57818
Alt Symbol	IGRP
Species	Human
Gene Type	protein-coding
Description	glucose-6-phosphatase, catalytic, 2
Other Description	G-6-Pase 2|G6Pase 2|glucose-6-phosphatase 2|islet-specific G6CP-related protein|islet-specific glucose-6-phosphatase catalytic subunit-related protein|islet-specific glucose-6-phosphatase-related protein
Swissprots	Q6AHZ0 Q9NQR9 E9PAX2
Accessions	AAF82810 AAY24099 EAX11291 Q9NQR9 AK310853 BC104778 AAI04779 BC113376 AAI13377 BQ268961 CA865646 CR627438 CAH10524 HQ258182 ADR82936 XM_011511564 XP_011509866 XM_011511565 XP_011509867 XM_011546941 XP_011545243 XM_011546942 XP_011545244 NM_001081686 NP_001075155 NM_021176 NP_066999
Function	May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:15044018}; Multi-pass membrane protein {ECO:0000269|PubMed:15044018}.
Tissue Specificity	Specifically expressed in pancreas and also detected to a lower extent in testis. Expressed by most islet cells in the pancreas (at protein level). {ECO:0000269|PubMed:11297555}.
Top Pathways	Glucagon signaling pathway, AMPK signaling pathway, PI3K-Akt signaling pathway, Carbohydrate digestion and absorption, Glycolysis / Gluconeogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IGRP CRISPR/Cas9 KO Plasmid (h) - sc-405436 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IGRP HDR Plasmid (h) - sc-405436-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IGRP Double Nickase Plasmid (h) - sc-405436-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IGRP Double Nickase Plasmid (h2) - sc-405436-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IGRP CRISPR Activation Plasmid (h) - sc-405436-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IGRP CRISPR Activation Plasmid (h2) - sc-405436-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IGRP Lentiviral Activation Particles (h) - sc-405436-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IGRP Lentiviral Activation Particles (h2) - sc-405436-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IGRP siRNA (h) - sc-45250 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IGRP shRNA Plasmid (h) - sc-45250-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IGRP shRNA (h) Lentiviral Particles - sc-45250-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU149951 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0235 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0962 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0236 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0961 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0237 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0960 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN9035 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9035 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10515 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10515

G6PC2 siRNA (Human) - CRJ1683 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

G6PC2 - MBS8207430 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human G6PC2 (NM_021176.2) - SHH298253 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human G6PC2(NM_001081686.1) - SHH072731 from Creative biogene Category siRNA Species Reactivities Human

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