ANO3

Gene Symbol ANO3
Entrez Gene 63982
Alt Symbol C11orf25, DYT23, DYT24, GENX-3947, TMEM16C
Species Human
Gene Type protein-coding
Description anoctamin 3
Other Description anoctamin-3|transmembrane protein 16C (eight membrane-spanning domains)
Swissprots Q9BYT9 B7Z3F5
Accessions EAW68296 Q9BYT9 AJ300461 CAC32454 AK295143 BAH11989 AK295658 BAH12144 AK295816 BAH12191 AK302659 BAH13772 AK304781 BAH14255 AK316018 BAH14389 BC172396 AAI72396 BQ430769 DA247850 HG503613 X81896 XM_011520282 XP_011518584 XM_011520283 XP_011518585 NM_031418 NP_113606
Function Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide. Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity. {ECO:0000250|UniProtKB:A2AHL1, ECO:0000269|PubMed:21984732}.
Subcellular Location Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Shows an intracellular localization. {ECO:0000250}.
Tissue Specificity Highly expressed in the forebrain striatum. {ECO:0000269|PubMed:23200863}.

TMEM16C CRISPR/Cas9 KO Plasmid (h) - sc-406106 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEM16C HDR Plasmid (h) - sc-406106-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEM16C Double Nickase Plasmid (h) - sc-406106-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEM16C Double Nickase Plasmid (h2) - sc-406106-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEM16C CRISPR Activation Plasmid (h) - sc-406106-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEM16C CRISPR Activation Plasmid (h2) - sc-406106-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEM16C Lentiviral Activation Particles (h) - sc-406106-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEM16C Lentiviral Activation Particles (h2) - sc-406106-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEM16C siRNA (h) - sc-96932 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TMEM16C shRNA Plasmid (h) - sc-96932-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TMEM16C shRNA (h) Lentiviral Particles - sc-96932-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU043361 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3243 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3243 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ANO3 siRNA (Human) - CRJ1892 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ANO3 - MBS8208166 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ANO3 (NM_031418.2) - SHH237322 from Creative biogene

Category siRNA
Species Reactivities Human

ANO3 shRNA Plasmid (Human) - CHJ1892 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ANO3 miRNA 3'UTR clone - MiUTR1H-10509 from Creative biogene

Species Reactivities Human
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