Gene Symbol | CCNT2 |
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Entrez Gene | 905 |
Alt Symbol | CYCT2 |
Species | Human |
Gene Type | protein-coding |
Description | cyclin T2 |
Other Description | SDS-stable vimentin-bound DNA fragment HEF42VIM22|cyclin T2a|cyclin T2b|cyclin-T2|subunit of positive elongation transcription factor b |
Swissprots | O60582 Q5I1Y0 D3DP74 O60583 Q53SR4 Q29R66 D3DP73 A8KA48 |
Accessions | AAW56073 AAY14998 EAX11644 EAX11645 EAX11646 EAX11647 O60583 AF048731 AAC39665 AF048732 AAC39666 AK023645 AK075041 AK292913 BAF85602 AK294889 BAG57982 AU157699 BC114366 AAI14367 BX648174 XM_006712827 XP_006712890 XM_011512132 XP_011510434 XM_011512133 XP_011510435 XM_011512134 XP_011510436 NM_001241 NP_001232 NM_058241 NP_490595 NR_037649 |
Function | Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II). {ECO:0000269|PubMed:10364329}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Ubiquitously expressed. |
Top Pathways | Transcriptional misregulation in cancer |
cyclin T2a (C-20) - sc-9530 from Santa Cruz Biotechnology
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cyclin T2b (C-18) - sc-9532 from Santa Cruz Biotechnology
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cyclin T2a/b (S-14) - sc-12421 from Santa Cruz Biotechnology
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cyclin T2a/b (A-20) - sc-12419 from Santa Cruz Biotechnology
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cyclin T2a/b (2128C1a) - sc-81243 from Santa Cruz Biotechnology
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Anti-Cyclin T2 antibody - ab96133 from Abcam
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Anti-Cyclin T2 antibody - ab34912 from Abcam
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Anti-Cyclin T2 antibody - ab89450 from Abcam
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Anti-Cyclin T2 antibody [2128C1a] - ab50979 from Abcam
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Anti-CCNT2 / Cyclin T2 Antibody - LS-C64127 from LifeSpan Bioscience
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Anti-CCNT2 / Cyclin T2 Antibody (clone 2128C1a) - LS-C184339 from LifeSpan Bioscience
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Anti-CCNT2 / Cyclin T2 Antibody (aa680-730) - LS-C288463 from LifeSpan Bioscience
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Anti-CCNT2 / Cyclin T2 Antibody (aa1-584) - LS-C18947 from LifeSpan Bioscience
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Anti-CCNT2 / Cyclin T2 Antibody (clone 1H3) - LS-C196835 from LifeSpan Bioscience
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Anti-CCNT2 / Cyclin T2 Antibody (clone 2128C1a) - LS-C342834 from LifeSpan Bioscience
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Anti-CCNT2 / Cyclin T2 Antibody (aa497-730) - LS-C186238 from LifeSpan Bioscience
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Cyclin T2 Antibody - NBP1-87592 from Novus Biologicals
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Cyclin T2 Antibody (1H3) - H00000905-M03 from Novus Biologicals
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Cyclin T2 Polyclonal Antibody - bs-7891R from Bioss
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Anti-CCNT2 (C-terminal) antibody produced in rabbit - SAB2701112 from Sigma-Aldrich
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Anti-CCNT2 antibody produced in rabbit - HPA005559 from Sigma-Aldrich
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Monoclonal Anti-CCNT2 antibody produced in mouse - SAB1401050 from Sigma-Aldrich
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Cyclin T2 antibody [C2C3], C-term - GTX111944 from GeneTex
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CCNT2 antibody - 10R-1301 from Fitzgerald
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Anti -CCNT2 (Cyclin T2, Cyclin-T2, CycT2, FLJ90560, MGC134840) - 124486 from USBiological Life Science
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