| Gene Symbol |
CCNT2
|
| Entrez Gene |
905
|
| Alt Symbol |
CYCT2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cyclin T2
|
| Other Description |
SDS-stable vimentin-bound DNA fragment HEF42VIM22|cyclin T2a|cyclin T2b|cyclin-T2|subunit of positive elongation transcription factor b
|
| Swissprots |
O60582 Q5I1Y0 D3DP74 O60583 Q53SR4 Q29R66 D3DP73 A8KA48
|
| Accessions |
AAW56073 AAY14998 EAX11644 EAX11645 EAX11646 EAX11647 O60583 AF048731 AAC39665 AF048732 AAC39666 AK023645 AK075041 AK292913 BAF85602 AK294889 BAG57982 AU157699 BC114366 AAI14367 BX648174 XM_006712827 XP_006712890 XM_011512132 XP_011510434 XM_011512133 XP_011510435 XM_011512134 XP_011510436 NM_001241 NP_001232 NM_058241 NP_490595 NR_037649
|
| Function |
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II). {ECO:0000269|PubMed:10364329}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Ubiquitously expressed.
|
| Top Pathways |
Transcriptional misregulation in cancer
|
![Western Blot: Cyclin T2 Overexpression Lysate (Adult Normal) [NBP2-10962] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cyclin T2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3771_Cyclin%2520T2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10962-img0001.jpg)