| Gene Symbol | CCNT2 |
|---|---|
| Entrez Gene | 905 |
| Alt Symbol | CYCT2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | cyclin T2 |
| Other Description | SDS-stable vimentin-bound DNA fragment HEF42VIM22|cyclin T2a|cyclin T2b|cyclin-T2|subunit of positive elongation transcription factor b |
| Swissprots | O60582 Q5I1Y0 D3DP74 O60583 Q53SR4 Q29R66 D3DP73 A8KA48 |
| Accessions | AAW56073 AAY14998 EAX11644 EAX11645 EAX11646 EAX11647 O60583 AF048731 AAC39665 AF048732 AAC39666 AK023645 AK075041 AK292913 BAF85602 AK294889 BAG57982 AU157699 BC114366 AAI14367 BX648174 XM_006712827 XP_006712890 XM_011512132 XP_011510434 XM_011512133 XP_011510435 XM_011512134 XP_011510436 NM_001241 NP_001232 NM_058241 NP_490595 NR_037649 |
| Function | Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II). {ECO:0000269|PubMed:10364329}. |
| Subcellular Location | Nucleus. |
| Tissue Specificity | Ubiquitously expressed. |
| Top Pathways | Transcriptional misregulation in cancer |