ELMO2

Gene Symbol ELMO2
Entrez Gene 63916
Alt Symbol CED-12, CED12, ELMO-2
Species Human
Gene Type protein-coding
Description engulfment and cell motility 2
Other Description PH domain protein CED12A|ced-12 homolog 2|engulfment and cell motility protein 2|hCed-12A|protein ced-12 homolog A
Swissprots Q7Z5G9 Q9HAH0 Q9H9L5 Q96CJ2 Q9NQQ6 E1P5T3 Q96ME5 Q5JVZ6 Q96PA9 Q96JJ3 Q9H938
Accessions EAW75739 EAW75743 EAW75745 EAW75746 Q96JJ3 AB058737 BAB47463 AF398886 AAL14467 AF417861 AAL38512 AK021718 BAB13879 AK022731 BAB14210 AK023103 BAB14405 AK057032 BAB71350 AK092796 AK293861 BAH11614 AK299318 BAG61327 AK302710 BAG63932 AL713765 AL833406 AM393730 CAL38605 AY947527 AAX21788 BC000143 AAH00143 BC014207 BC021079 BC036483 BX648819 XM_005260496 XP_005260553 XM_005260497 XP_005260554 XM_005260498 XP_005260555 XM_005260499 XP_005260556 XM_005260500 XP_005260557 XM_005260501 XP_005260558 XM_005260502 XP_005260559 XM_006723854 XP_006723917 NM_133171 NP_573403 NM_182764 NP_877496 NM_022086
Function Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. {ECO:0000269|PubMed:11595183, ECO:0000269|PubMed:11703939, ECO:0000269|PubMed:20679435}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20679435}. Cytoplasm, cytosol {ECO:0000269|PubMed:20679435}. Membrane {ECO:0000269|PubMed:20679435}.
Tissue Specificity Widely expressed, with a higher expression in skeletal muscle, kidney and placenta. {ECO:0000269|PubMed:11595183}.
Top Pathways Bacterial invasion of epithelial cells

Elmo2 (C-12) - sc-365739 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Elmo2 (C-12): sc-365739. Western blot analysis of Elmo2 expression in Jurkat (A), CTLL-2 (B) and TK-1 (C) whole cell lysates.

Elmo2 (E-16) - sc-21655 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Elmo2 (E-16): sc-21655. Western blot analysis of Elmo2 expression in Jurkat whole cell lysate.

Elmo2 (M-551) - sc-21004 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Elmo2 (M-551): sc-21004. Western blot analysis of Elmo2 expression in Jurkat whole cell lysate.

Elmo2 (S-14) - sc-31909 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Elmo2 (S-14): sc-31909. Western blot analysis of Elmo2 expression in Jurkat whole cell lysate.

Elmo2 (I-18) - sc-31908 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ELMO2 antibody - ab107279 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ELMO2 antibody (ab107279) at 1/100 dilution + Jurkat cell line lysate at 35 µg

Anti-ELMO2 antibody [EPR13567] - ab181234 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13567
All lanes : Anti-ELMO2 antibody [EPR13567] (ab181234) at 1/2000 dilutionLane 1 : Jurkat cell lysateLane 2 : HeLa cell lysateLane 3 : Human fetal brain lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-ELMO2 antibody - C-terminal - ab154966 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ELMO2 antibody - C-terminal (ab154966) at 1/500 dilutionLane 1 : Non-transfected 293T cell lysateLane 2 : ELMO2-transfected 293T cell Lysate

Anti-ELMO2 Antibody (aa323-350, AP) - LS-C234913 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO2 Antibody (aa323-350, Biotin) - LS-C234915 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO2 Antibody (aa323-350, APC) - LS-C234914 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO2 Antibody (aa323-350, PE) - LS-C234920 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO2 Antibody (aa323-350, FITC) - LS-C234916 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO2 Antibody (aa323-350, Azide-free, HRP) - LS-C249902 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO2 Antibody (clone M1-C8) - LS-C307405 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone M1-C8

Anti-ELMO2 Antibody (aa330-357) - LS-C321094 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELMO2 Antibody (aa323-350) - LS-C167734 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ELMO2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-ELMO2 Antibody (aa707-720) IHC-plus™ - LS-B4921 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-ELMO2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4921 concentration 3.75 ug/ml.

ELMO2 Antibody - NB100-879 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

ELMO2 Antibody - NBP2-16318 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ELMO2 Antibody [NBP2-16318] - Western Blot analysis of ELMO2 expression in transfected 293T cell line by ELMO2 polyclonal antibody. A: Non-transfected lysate. B: ELMO2 transfected lysate. 12% SDS PAGE gel, diluted at 1:500.

ELMO2 Antibody - NBP1-84554 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ELMO2 Antibody [NBP1-84554] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11Lane 2: Human cell line RT-4Lane 3: Human cell line U-251MG spLane 4: Human plasma (IgG/HSA depleted)

ELMO2 Antibody - NBP2-16317 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ELMO2 Antibody [NBP2-16317] - Sample (30 ug of whole cell lysate) A: Raji 7. 5% SDS PAGE gel, diluted at 1:500.

ELMO2 Antibody - H00063916-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: ELMO2 Antibody [H00063916-B01] - analysis of ELMO2 expression in transfected 293T cell line by ELMO2 MaxPab polyclonal antibody (B01). Lane 1: ELMO2 transfected lysate (82.60 KDa). Lane 2: Non-transfected lysate.

ELMO2 Antibody (3G7) - H00063916-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G7
Sandwich ELISA: ELMO2 Antibody (3G7) [H00063916-M02] - Detection limit for recombinant GST tagged ELMO2 is 0.1 ng/ml as a capture antibody.

ELMO2 Antibody (2E5) - H00063916-M07 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E5
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