ELMO2

Gene Symbol ELMO2
Entrez Gene 63916
Alt Symbol CED-12, CED12, ELMO-2
Species Human
Gene Type protein-coding
Description engulfment and cell motility 2
Other Description PH domain protein CED12A|ced-12 homolog 2|engulfment and cell motility protein 2|hCed-12A|protein ced-12 homolog A
Swissprots Q7Z5G9 Q9HAH0 Q9H9L5 Q96CJ2 Q9NQQ6 E1P5T3 Q96ME5 Q5JVZ6 Q96PA9 Q96JJ3 Q9H938
Accessions EAW75739 EAW75743 EAW75745 EAW75746 Q96JJ3 AB058737 BAB47463 AF398886 AAL14467 AF417861 AAL38512 AK021718 BAB13879 AK022731 BAB14210 AK023103 BAB14405 AK057032 BAB71350 AK092796 AK293861 BAH11614 AK299318 BAG61327 AK302710 BAG63932 AL713765 AL833406 AM393730 CAL38605 AY947527 AAX21788 BC000143 AAH00143 BC014207 BC021079 BC036483 BX648819 XM_005260496 XP_005260553 XM_005260497 XP_005260554 XM_005260498 XP_005260555 XM_005260499 XP_005260556 XM_005260500 XP_005260557 XM_005260501 XP_005260558 XM_005260502 XP_005260559 XM_006723854 XP_006723917 NM_133171 NP_573403 NM_182764 NP_877496 NM_022086
Function Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. {ECO:0000269|PubMed:11595183, ECO:0000269|PubMed:11703939, ECO:0000269|PubMed:20679435}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20679435}. Cytoplasm, cytosol {ECO:0000269|PubMed:20679435}. Membrane {ECO:0000269|PubMed:20679435}.
Tissue Specificity Widely expressed, with a higher expression in skeletal muscle, kidney and placenta. {ECO:0000269|PubMed:11595183}.
Top Pathways Bacterial invasion of epithelial cells

Elmo2 CRISPR/Cas9 KO Plasmid (h) - sc-405182 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo2 HDR Plasmid (h) - sc-405182-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo2 Double Nickase Plasmid (h) - sc-405182-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo2 Double Nickase Plasmid (h2) - sc-405182-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo2 CRISPR Activation Plasmid (h) - sc-405182-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo2 CRISPR Activation Plasmid (h2) - sc-405182-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo2 Lentiviral Activation Particles (h) - sc-405182-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo2 Lentiviral Activation Particles (h2) - sc-405182-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Elmo2 siRNA (h) - sc-40527 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Elmo2 shRNA Plasmid (h) - sc-40527-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Elmo2 shRNA (h) Lentiviral Particles - sc-40527-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ELMO2 RNAi - H00063916-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU145581 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7813 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7813 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ELMO2 siRNA (Human) - CRJ1859 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ELMO2 RNAi - H00063916-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ELMO2 - MBS8217022 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ELMO2 (NM_182764.1) - SHH285161 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ELMO2(NM_133171.3) - SHG210025 from Creative biogene

Category siRNA
Species Reactivities Human

ELMO2 shRNA Plasmid (Human) - CHJ1859 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ELMO2 miRNA 3'UTR clone - MiUTR1H-03198 from Creative biogene

Species Reactivities Human

ELMO2 miRNA 3'UTR clone - MiUTR3H-08439 from Creative biogene

Species Reactivities Human
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