ELMO2

Gene Symbol	ELMO2
Entrez Gene	63916
Alt Symbol	CED-12, CED12, ELMO-2
Species	Human
Gene Type	protein-coding
Description	engulfment and cell motility 2
Other Description	PH domain protein CED12A|ced-12 homolog 2|engulfment and cell motility protein 2|hCed-12A|protein ced-12 homolog A
Swissprots	Q7Z5G9 Q9HAH0 Q9H9L5 Q96CJ2 Q9NQQ6 E1P5T3 Q96ME5 Q5JVZ6 Q96PA9 Q96JJ3 Q9H938
Accessions	EAW75739 EAW75743 EAW75745 EAW75746 Q96JJ3 AB058737 BAB47463 AF398886 AAL14467 AF417861 AAL38512 AK021718 BAB13879 AK022731 BAB14210 AK023103 BAB14405 AK057032 BAB71350 AK092796 AK293861 BAH11614 AK299318 BAG61327 AK302710 BAG63932 AL713765 AL833406 AM393730 CAL38605 AY947527 AAX21788 BC000143 AAH00143 BC014207 BC021079 BC036483 BX648819 XM_005260496 XP_005260553 XM_005260497 XP_005260554 XM_005260498 XP_005260555 XM_005260499 XP_005260556 XM_005260500 XP_005260557 XM_005260501 XP_005260558 XM_005260502 XP_005260559 XM_006723854 XP_006723917 NM_133171 NP_573403 NM_182764 NP_877496 NM_022086
Function	Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. {ECO:0000269|PubMed:11595183, ECO:0000269|PubMed:11703939, ECO:0000269|PubMed:20679435}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:20679435}. Cytoplasm, cytosol {ECO:0000269|PubMed:20679435}. Membrane {ECO:0000269|PubMed:20679435}.
Tissue Specificity	Widely expressed, with a higher expression in skeletal muscle, kidney and placenta. {ECO:0000269|PubMed:11595183}.
Top Pathways	Bacterial invasion of epithelial cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ELMO2 full length protein - ab131840 from Abcam Category Protein Source Wheat germ Species Human

Human ELMO2 peptide - ab22879 from Abcam Category Peptide Species Human

ELMO2 Antibody Blocking Peptide - LS-E749 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ELMO2 Antibody Blocking Peptide - LS-E25296 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ELMO2 Protein - H00063916-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ELMO2 Protein - H00063916-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ELMO2-Antibody-Center-Blocking-peptide - BP11106c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ELMO2 blocking peptide - GTX89956-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat, Bovine

ELMO2 Immunizing peptide - orb17624 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

ELMO2 Peptide - AC21-0124-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ELMO2 - H00063916-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ELMO2 - H00063916-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ELMO2 - H00063916-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ELMO2 - H00063916-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ELMO2 Peptide - 45-531P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

ELMO2 fusion protein - ag1266 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Engulfment and cell motility protein 2(ELMO2) - CSB-YP836237HU CSB-EP836237HU CSB-BP836237HU CSB-MP836237HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ELMO2 (transcript variant 1) - TP316889 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ELMO2 (transcript variant 2) - TP322021 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ELMO2, Peptide - MBS426396 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

Recombinant Engulfment And Cell Motility 2 (ELMO2) - RPC454Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Engulfment And Cell Motility 2 (ELMO2) - RPC454Hu01 from Cloud-clone Category Protein Source E.coli Species Human

ELMO2 Recombinant Protein Antigen - NBP1-84554PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

ELMO2 Peptide, Human - M34GP04867H from Creative Peptides Category Peptide Source Synthetic. Species Human

ELMO2 fusion protein - Ag25832 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

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