IRX5

Gene Symbol	IRX5
Entrez Gene	10265
Alt Symbol	HMMS, IRX-2a, IRXB2
Species	Human
Gene Type	protein-coding
Description	iroquois homeobox 5
Other Description	homeodomain protein IRX-2A|homeodomain protein IRXB2|iroquois-class homeodomain protein IRX-5
Swissprots	Q7Z2E1 P78411 P78416 H0YMS7
Accessions	AAQ16550 CBX47594 P78411 AY335945 AAQ16551 BC074850 BC131510 AAI31511 U90304 AAB50002 U90309 AAB50007 XM_011522809 XP_011521111 NM_001252197 NP_001239126 NM_005853 NP_005844
Function	Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells. Involved in craniofacial and gonadal development. Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12. {ECO:0000250, ECO:0000269|PubMed:22581230}.
Subcellular Location	Nucleus {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human IRX5 protein fragment - ab160911 from Abcam Category Protein Source Wheat germ Species Human

IRX5 Antibody Blocking Peptide - LS-E4358 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IRX5 Antibody Blocking Peptide - LS-E13353 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Iroquois-class homeodomain protein IRX-5 Protein - H00010265-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

IRX5-Antibody-C-term-Blocking-Peptide - BP16657b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

IRX5 / IRXB2 - H00010265-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

IRX5 / IRXB2 - H00010265-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human Iroquois-class homeodomain protein IRX-5(IRX5) - CSB-YP011837HU CSB-EP011837HU CSB-BP011837HU CSB-MP011837HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Irx5, Peptide - MBS659805 from MyBioSource Category Peptide Prices $290.00 Sizes 1 mg Species Human, Rodent

Irx5, Peptide - MBS658058 from MyBioSource Category Peptide Prices $290.00 Sizes 1 mg Species Human, Rodent

Iroquois-class homeodomain protein IRX-5 Protein - NBP1-92029PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

IRX5 Peptide, Human - M34GP07757H from Creative Peptides Category Peptide Source Synthetic. Species Human

Iroquois-class homeodomain protein IRX-5 (IRX5), Recombinant Protein - MBS718206 from MyBioSource Category Protein Prices $1,265.00, $1,265.00, $1,485.00, $1,485.00, $2,075.00, $2,075.00, $2,540.00, $2,540.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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