IRX5

Gene Symbol	IRX5
Entrez Gene	10265
Alt Symbol	HMMS, IRX-2a, IRXB2
Species	Human
Gene Type	protein-coding
Description	iroquois homeobox 5
Other Description	homeodomain protein IRX-2A|homeodomain protein IRXB2|iroquois-class homeodomain protein IRX-5
Swissprots	Q7Z2E1 P78411 P78416 H0YMS7
Accessions	AAQ16550 CBX47594 P78411 AY335945 AAQ16551 BC074850 BC131510 AAI31511 U90304 AAB50002 U90309 AAB50007 XM_011522809 XP_011521111 NM_001252197 NP_001239126 NM_005853 NP_005844
Function	Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells. Involved in craniofacial and gonadal development. Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12. {ECO:0000250, ECO:0000269|PubMed:22581230}.
Subcellular Location	Nucleus {ECO:0000305}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

IRX5 CRISPR/Cas9 KO Plasmid (h) - sc-404838 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRX5 HDR Plasmid (h) - sc-404838-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRX5 Double Nickase Plasmid (h) - sc-404838-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRX5 Double Nickase Plasmid (h2) - sc-404838-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRX5 CRISPR Activation Plasmid (h) - sc-404838-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRX5 CRISPR Activation Plasmid (h2) - sc-404838-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRX5 Lentiviral Activation Particles (h) - sc-404838-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRX5 Lentiviral Activation Particles (h2) - sc-404838-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IRX5 siRNA (h) - sc-93469 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IRX5 shRNA Plasmid (h) - sc-93469-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IRX5 shRNA (h) Lentiviral Particles - sc-93469-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Iroquois-class homeodomain protein IRX-5 RNAi - H00010265-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU035261 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10781 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10781 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

IRX5 siRNA (Human) - CRH6948 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

IRX5 - MBS8208127 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

IRX5 CRISPR/Cas9 KO Plasmid (h2) - sc-404838-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IRX5 HDR Plasmid (h2) - sc-404838-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human IRX5 (NM_005853.5) - SHH320845 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human IRX5(NM_005853.5) - SHL174054 from Creative biogene Category siRNA Species Reactivities Human

Human IRX5 siRNA - orb267450 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

IRX5 shRNA Plasmid (Human) - CHH6948 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

IRX5 miRNA 3'UTR clone - MiUTR1H-05003 from Creative biogene Species Reactivities Human

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