Gene Symbol | ITSN2 |
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Entrez Gene | 50618 |
Alt Symbol | PRO2015, SH3D1B, SH3P18, SWA, SWAP |
Species | Human |
Gene Type | protein-coding |
Description | intersectin 2 |
Other Description | SH3 domain-containing protein 1B|SH3P18-like WASP-associated protein|intersectin-2 |
Swissprots | Q9HAK4 O95062 Q9NZM3 Q9NYG0 Q9NXE6 Q9NZM2 Q15812 Q9ULG4 |
Accessions | AAX93122 AAX93123 AAY14668 EAX00750 EAX00751 EAX00752 EAX00753 Q9NZM3 AB033082 BAA86570 AF001630 AAD00899 AF038189 AF182198 AAF59903 AF182199 AAF59904 AF248540 AAF63600 AK000302 BAA91068 AK021545 BAB13841 AK025400 AK091859 BC020921 AAH20921 BC038963 AAH38963 BC146779 AAI46780 DA382952 U61167 AAC50593 NM_006277 NP_006268 NM_019595 NP_062541 NM_147152 NP_671494 |
Function | Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). {ECO:0000269|PubMed:19458185, ECO:0000269|PubMed:22648170}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Ubiquitous. Isoform 1 is primarily expressed in adult heart and liver. |
Intersectin-2 (T-19) - sc-9952 from Santa Cruz Biotechnology
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Intersectin-2 (H-16) - sc-9953 from Santa Cruz Biotechnology
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Intersectin-2 L (I-17) - sc-9955 from Santa Cruz Biotechnology
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Intersectin-2 L (M-16) - sc-9954 from Santa Cruz Biotechnology
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Anti-Intersectin-2 antibody - ab176592 from Abcam
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Anti-Intersectin-2 antibody - ab122343 from Abcam
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Anti-Intersectin-2 antibody - ab133854 from Abcam
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Anti-ITSN2 Antibody (aa1447-1453) - LS-C3156 from LifeSpan Bioscience
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Anti-ITSN2 Antibody (aa1001-1050) - LS-C151984 from LifeSpan Bioscience
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Anti-ITSN2 Antibody (aa550-600) - LS-C289778 from LifeSpan Bioscience
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Intersectin 2 Antibody - NBP1-71833 from Novus Biologicals
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Intersectin 2 Antibody - H00050618-A01 from Novus Biologicals
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Intersectin 2 Antibody - NBP1-89610 from Novus Biologicals
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Rabbit Anti-Intersectin 2 Polyclonal Antibody - bs-13646R from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13646R-A350 from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13646R-A488 from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13646R-A555 from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13646R-A647 from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, Cy3 Conjugated - bs-13646R-Cy3 from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, Cy5 Conjugated - bs-13646R-Cy5 from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, Cy5.5 Conjugated - bs-13646R-Cy5.5 from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, Cy7 Conjugated - bs-13646R-Cy7 from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, FITC Conjugated - bs-13646R-FITC from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, Biotin Conjugated - bs-13646R-Biotin from Bioss
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Rabbit Anti-Intersectin 2 Polyclonal Antibody, HRP Conjugated - bs-13646R-HRP from Bioss
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