ITSN2

Gene Symbol ITSN2
Entrez Gene 50618
Alt Symbol PRO2015, SH3D1B, SH3P18, SWA, SWAP
Species Human
Gene Type protein-coding
Description intersectin 2
Other Description SH3 domain-containing protein 1B|SH3P18-like WASP-associated protein|intersectin-2
Swissprots Q9HAK4 O95062 Q9NZM3 Q9NYG0 Q9NXE6 Q9NZM2 Q15812 Q9ULG4
Accessions AAX93122 AAX93123 AAY14668 EAX00750 EAX00751 EAX00752 EAX00753 Q9NZM3 AB033082 BAA86570 AF001630 AAD00899 AF038189 AF182198 AAF59903 AF182199 AAF59904 AF248540 AAF63600 AK000302 BAA91068 AK021545 BAB13841 AK025400 AK091859 BC020921 AAH20921 BC038963 AAH38963 BC146779 AAI46780 DA382952 U61167 AAC50593 NM_006277 NP_006268 NM_019595 NP_062541 NM_147152 NP_671494
Function Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). {ECO:0000269|PubMed:19458185, ECO:0000269|PubMed:22648170}.
Subcellular Location Cytoplasm.
Tissue Specificity Ubiquitous. Isoform 1 is primarily expressed in adult heart and liver.

Human Intersectin-2 protein fragment - ab162345 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162345 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ITSN2 Antibody Blocking Peptide - LS-E23830 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Intersectin 2 Protein - H00050618-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

SWAP Blocking Peptide - abx063254 from Abbexa

Category Peptide
Species Human, Mouse, Rat

Intersectin-2 / ITSN2 - H00050618-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Intersectin-2 / ITSN2 - H00050618-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

ITSN2 fusion protein - ag20130 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human
ITSN2 fusion protein ag20130 SDS-PAGE

ITSN2 fusion protein - ag20273 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human ITSN2, GST-tagged - ITSN2-193H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Intersectin-2(ITSN2) ,partial - CSB-YP873709HU CSB-EP873709HU CSB-BP873709HU CSB-MP873709HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Intersectin 2 Recombinant Protein Antigen - NBP1-89610PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

ITSN2 Peptide, Human - M34GP07837H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Intersectin-2 (ITSN2), partial, Recombinant Protein - MBS1285792 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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