| Gene Symbol |
HSD17B14
|
| Entrez Gene |
51171
|
| Alt Symbol |
DHRS10, SDR47C1, retSDR3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
hydroxysteroid (17-beta) dehydrogenase 14
|
| Other Description |
17-beta-HSD 14|17-beta-hydroxysteroid dehydrogenase 14|17-beta-hydroxysteroid dehydrogenase DHRS10|dehydrogenase/reductase (SDR family) member 10|dehydrogenase/reductase SDR family member 10|retinal short-chain dehydrogenase/reductase 3|retinal short-chain dehydrogenase/reductase retSDR3|short chain dehydrogenase/reductase family 47C member 1|short chain dehydrogenase/reductase family 47C, member 1
|
| Swissprots |
Q9UKU3 Q9BPX1
|
| Accessions |
EAW52404 Q9BPX1 AF126781 AAF06940 AK307437 AY358430 AAQ88796 BC006283 AAH06283 BC006294 AAH06294 BI602824 HQ448038 ADQ32519 XM_005258969 XP_005259026 XM_005258970 XP_005259027 XR_243938 NM_016246 NP_057330
|
| Function |
Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro). {ECO:0000269|PubMed:17067289}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17067289}.
|
| Tissue Specificity |
Highly expressed in brain, placenta, liver and kidney. {ECO:0000269|PubMed:10800688, ECO:0000269|PubMed:17067289}.
|
![Western Blot: HSD17B14 Overexpression Lysate (Adult Normal) [NBP2-07063] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HSD17B14.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8345_HSD17B14%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07063-img0001.jpg)