Gene Symbol | HSD17B14 |
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Entrez Gene | 51171 |
Alt Symbol | DHRS10, SDR47C1, retSDR3 |
Species | Human |
Gene Type | protein-coding |
Description | hydroxysteroid (17-beta) dehydrogenase 14 |
Other Description | 17-beta-HSD 14|17-beta-hydroxysteroid dehydrogenase 14|17-beta-hydroxysteroid dehydrogenase DHRS10|dehydrogenase/reductase (SDR family) member 10|dehydrogenase/reductase SDR family member 10|retinal short-chain dehydrogenase/reductase 3|retinal short-chain dehydrogenase/reductase retSDR3|short chain dehydrogenase/reductase family 47C member 1|short chain dehydrogenase/reductase family 47C, member 1 |
Swissprots | Q9UKU3 Q9BPX1 |
Accessions | EAW52404 Q9BPX1 AF126781 AAF06940 AK307437 AY358430 AAQ88796 BC006283 AAH06283 BC006294 AAH06294 BI602824 HQ448038 ADQ32519 XM_005258969 XP_005259026 XM_005258970 XP_005259027 XR_243938 NM_016246 NP_057330 |
Function | Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro). {ECO:0000269|PubMed:17067289}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17067289}. |
Tissue Specificity | Highly expressed in brain, placenta, liver and kidney. {ECO:0000269|PubMed:10800688, ECO:0000269|PubMed:17067289}. |
17β-HSD14 (S-12) - sc-131361 from Santa Cruz Biotechnology
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Anti-HSD17B14 antibody - ab198013 from Abcam
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Anti-HSD17B14 antibody - ab87011 from Abcam
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Anti-HSD17B14 antibody - ab67465 from Abcam
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Anti-HSD17B14 Antibody (aa2-270, clone 12K104) - LS-C182873 from LifeSpan Bioscience
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Anti-HSD17B14 Antibody - LS-C308320 from LifeSpan Bioscience
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Anti-HSD17B14 Antibody (aa35-84) - LS-C108030 from LifeSpan Bioscience
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Anti-HSD17B14 Antibody (C-Terminus) - LS-C102719 from LifeSpan Bioscience
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17 beta-HSD14/HSD17B14 Antibody (736043) - MAB7515 from Novus Biologicals
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17 beta-HSD14/HSD17B14 Antibody - NBP1-85220 from Novus Biologicals
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17 beta-HSD14/HSD17B14 Antibody - NBP1-56863 from Novus Biologicals
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17 beta-HSD14/HSD17B14 Antibody - NBP1-57625 from Novus Biologicals
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17 beta-HSD14/HSD17B14 Antibody - H00051171-B01P from Novus Biologicals
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17 beta-HSD14/HSD17B14 Antibody - H00051171-B01 from Novus Biologicals
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Anti-HSD17B14 antibody produced in mouse - SAB1407452 from Sigma-Aldrich
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Anti-HSD17B14, (N-terminal) antibody produced in rabbit - SAB2106013 from Sigma-Aldrich
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Anti-HSD17B14 antibody produced in rabbit - HPA021467 from Sigma-Aldrich
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HSD17B14 antibody - N-terminal region (ARP56864_P050) - ARP56864_P050 from Aviva Systems Biology
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HSD17B14 antibody - middle region (ARP56865_P050) - ARP56865_P050 from Aviva Systems Biology
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HSD17B14 antibody, Internal - GTX45014 from GeneTex
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HSD17B14 antibody, N-term - GTX45015 from GeneTex
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Human 17 beta -HSD14/HSD17B14 Antibody - MAB7515 from R&D Systems
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Human 17 beta-HSD14 MAb (Clone 736043), Mouse IgG2B - MAB7515-SP from R&D Systems
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Anti -HSD17B14 (17-beta-hydroxysteroid Dehydrogenase 14, 17-beta-HSD 14,17-beta-hydroxysteroid Dehydrogenase DHRS10, Dehydrogenase/Reductase SDR Family Member 10,Retinal Short-chain Dehydrogenase/Reductase retSDR3, DHRS10, SDR3, UNQ502/PRO474) - H9117-83E from USBiological Life Science
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Anti -HSD17B14 (17-beta-hydroxysteroid Dehydrogenase 14, 17-beta-HSD 14,17-beta-hydroxysteroid Dehydrogenase DHRS10, Dehydrogenase/Reductase SDR Family Member 10,Retinal Short-chain Dehydrogenase/Reductase retSDR3, DHRS10, SDR3, UNQ502/PRO474) - 128087 from USBiological Life Science
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