HSD17B14

Gene Symbol HSD17B14
Entrez Gene 51171
Alt Symbol DHRS10, SDR47C1, retSDR3
Species Human
Gene Type protein-coding
Description hydroxysteroid (17-beta) dehydrogenase 14
Other Description 17-beta-HSD 14|17-beta-hydroxysteroid dehydrogenase 14|17-beta-hydroxysteroid dehydrogenase DHRS10|dehydrogenase/reductase (SDR family) member 10|dehydrogenase/reductase SDR family member 10|retinal short-chain dehydrogenase/reductase 3|retinal short-chain dehydrogenase/reductase retSDR3|short chain dehydrogenase/reductase family 47C member 1|short chain dehydrogenase/reductase family 47C, member 1
Swissprots Q9UKU3 Q9BPX1
Accessions EAW52404 Q9BPX1 AF126781 AAF06940 AK307437 AY358430 AAQ88796 BC006283 AAH06283 BC006294 AAH06294 BI602824 HQ448038 ADQ32519 XM_005258969 XP_005259026 XM_005258970 XP_005259027 XR_243938 NM_016246 NP_057330
Function Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro). {ECO:0000269|PubMed:17067289}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17067289}.
Tissue Specificity Highly expressed in brain, placenta, liver and kidney. {ECO:0000269|PubMed:10800688, ECO:0000269|PubMed:17067289}.

17β-HSD14 (S-12) - sc-131361 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-HSD17B14 antibody - ab198013 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue labeling HSD17B14 with ab198013 at 1/30 dilution.

Anti-HSD17B14 antibody - ab87011 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HSD17B14 antibody (ab87011) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal liver lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-HSD17B14 antibody - ab67465 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-HSD17B14 antibody (ab67465) at 1/500 dilutionLane 1 : HSD17B14 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg/ml per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-HSD17B14 Antibody (aa2-270, clone 12K104) - LS-C182873 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 12K104

Anti-HSD17B14 Antibody - LS-C308320 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HSD17B14 Antibody (aa35-84) - LS-C108030 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HSD17B14 antibody LS-C108030 Western blot of Fetal Small Intestine lysate.

Anti-HSD17B14 Antibody (C-Terminus) - LS-C102719 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HSD17B14 antibody LS-C102719 Western blot of Fetal Liver lysate.

17 beta-HSD14/HSD17B14 Antibody (736043) - MAB7515 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 736043
Immunohistochemistry 17 beta-HSD14/HSD17B14 Antibody (736043)

17 beta-HSD14/HSD17B14 Antibody - NBP1-85220 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HSD17B14 Antibody [NBP1-85220] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY414089)

17 beta-HSD14/HSD17B14 Antibody - NBP1-56863 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: 17 beta-HSD14/HSD17B14 Antibody [NBP1-56863] - Human Small Intestine, concentration 0.2-1 ug/ml.

17 beta-HSD14/HSD17B14 Antibody - NBP1-57625 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: 17 beta-HSD14/HSD17B14 Antibody [NBP1-57625] - Titration: 0.2-1 ug/ml, Positive Control: Human Liver.

17 beta-HSD14/HSD17B14 Antibody - H00051171-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

17 beta-HSD14/HSD17B14 Antibody - H00051171-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: 17 beta-HSD14/HSD17B14 Antibody [H00051171-B01] - analysis of DHRS10 expression in transfected 293T cell line by DHRS10 MaxPab polyclonal antibody (B01). Lane 1: DHRS10 transfected lysate (28.30 KDa). Lane 2: Non-transfected lysate.

Anti-HSD17B14 antibody produced in mouse - SAB1407452 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HSD17B14: <B>Cat. No. SAB1407452</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~29.7 kDa using HSD17B14 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-HSD17B14, (N-terminal) antibody produced in rabbit - SAB2106013 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HSD17B14 (N-Terminal): <B>Cat. No. SAB2106013</B>: HSD17B14 in Fetal Small Intestine cell lysates with HSD17B14 antibody at 1.0 μg/mL.

Anti-HSD17B14 antibody produced in rabbit - HPA021467 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HSD17B14: <B>Cat. No. HPA021467</B>: Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in Chief cells.

HSD17B14 antibody - N-terminal region (ARP56864_P050) - ARP56864_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HSD17B14 antibody - middle region (ARP56865_P050) - ARP56865_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HSD17B14 antibody, Internal - GTX45014 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-HSD17B14 antibody, Internal used in Western blot. GTX45014

HSD17B14 antibody, N-term - GTX45015 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-HSD17B14 antibody, N-term used in Western blot. GTX45015

Human 17 beta -HSD14/HSD17B14 Antibody - MAB7515 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 736043
17 beta -HSD14/HSD17B14 in Human Brain. 17 beta -HSD14/HSD17B14 was detected in immersion fixed paraffin-embedded sections of human brain (medulla) using Mouse Anti-Human 17 beta -HSD14/HSD17B14 Monoclonal Antibody (Catalog # MAB7515) at 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013 ). Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002 ) and counterstained with hematoxylin (blue). Specific staining was localized to neuronal cytoplasm. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections .

Human 17 beta-HSD14 MAb (Clone 736043), Mouse IgG2B - MAB7515-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 736043
17 beta ‑HSD14/HSD17B14 in Human Brain.  17 beta ‑HSD14/HSD17B14 was detected in immersion fixed paraffin-embedded sections of human brain (medulla) using Mouse Anti-Human 17 beta ‑HSD14/HSD17B14 Monoclonal Antibody (Catalog # MAB7515) at 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific staining was localized to neuronal cytoplasm. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
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