HNRNPC

Gene Symbol	HNRNPC
Entrez Gene	3183
Alt Symbol	C1, C2, HNRNP, HNRPC, SNRPC
Species	Human
Gene Type	protein-coding
Description	heterogeneous nuclear ribonucleoprotein C (C1/C2)
Other Description	heterogeneous nuclear ribonucleoproteins C1/C2|hnRNP C1/C2|nuclear ribonucleoprotein particle C1 protein|nuclear ribonucleoprotein particle C2 protein
Swissprots	P07910 Q86U45 Q86SF8 Q59FD3 Q53EX2 D3DS19 Q96IY5 D3DS22 Q9BTS3 Q96HK7 P22628 Q5FWE8 Q96HM4
Accessions	CAH05635 EAW66392 EAW66393 EAW66394 EAW66395 EAW66396 EAW66397 EAW66398 EAW66399 EAW66400 P07910 AB209527 BAD92764 AK126950 BAG54408 AK223517 BAD97237 AK225032 AK292619 BAF85308 AK297482 BAG59903 AK298906 BAG61014 AK299923 BAG61758 AK302213 BAG63570 AK312338 BAG35259 AK312382 BAG35300 AL833432 BC003394 AAH03394 BC007052 AAH07052 BC008364 AAH08364 BC008423 AAH08423 BC066932 AAH66932 BC071943 BC089438 AAH89438 BC092433 AAH92433 BC103758 AAI03759 BC108658 AAI08659 BX161480 CAD61934 BX247961 CAD62300 BX247992 CAD62326 D28382 BAA05748 DB449514 HQ258021 ADR82775 M16342 AAA52680 M29063 AAA36576 Z70766 XM_006720125 XP_006720188 XM_011536708 XP_011535010 XM_011536709 XP_011535011 XM_011536710 XP_011535012 XM_011536711 XP_011535013 XM_011536712 XP_011535014 NM_001077442 NP_001070910 NM_001077443 NP_001070911 NM_004500 NP_004491 NM_031314 NP_112604
Function	Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. {ECO:0000269|PubMed:12509468, ECO:0000269|PubMed:16010978, ECO:0000269|PubMed:7567451, ECO:0000269|PubMed:8264621}.
Subcellular Location	Nucleus. Note=Component of ribonucleosomes.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human hnRNP C1 + C2 full length protein - ab104668 from Abcam Category Protein Source E. coli Species Human

Human hnRNP C1 + C2 full length protein - ab125177 from Abcam Category Protein Source E. coli Species Human

HNRNPC / HNRNP C Antibody Blocking Peptide - LS-E445 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HNRNPC / HNRNP C Antibody Blocking Peptide - LS-E14799 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HNRNPC / HNRNP C Antibody Blocking Peptide - LS-E14798 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HNRNPC / HNRNP C Antibody Blocking Peptide - LS-E25041 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HNRNPC / HNRNP C Antibody Blocking Peptide - LS-E25042 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SNRPC / U1C Antibody Blocking Peptide - LS-E7142 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Complement Component C2 Protein - H00000717-P02 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

SNRPC Recombinant Protein - H00006631-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

hnRNP C1 + C2 Recombinant Protein - H00003183-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Complement Component C2 Protein - H00000717-Q01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human hnRNP C1 + C2 Protein - NBP1-51035 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 10 µg, 50 µg Source E. coli Species Human

Recombinant Human SNRPC Protein - NBP1-78822 from Novus Biologicals Category Protein Prices $269.00 Sizes 10 µg Source E. coli Species Human

HNRNPC-Antibody-C-term-Blocking-peptide - BP10728b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HNRNPC Protein (OPPA00184) - OPPA00184 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 1 µg Source Escherichia Coli.

Human C2 Fc tag protein - orb82880 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Human Species Human

Human SNRPC protein - orb169322 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source Sf9 insect cells.

Human C2 His tag protein - orb82879 from Biorbyt Category Protein Prices $510.00, $748.00 Sizes 10 μg, 20 μg Source Human Species Human

Human HNRNPC protein - orb168508 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 1 μg, 5 μg, 50 μg Source E. coli

Human SNRPC protein - orb169321 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 1 μg, 5 μg, 50 μg Species Human

HNRNPC Blocking Peptide - 33R-2723 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HNRNPC protein (His tag) - 80R-1723 from Fitzgerald Category Protein Prices $255.00 Sizes 10 µg Source E.coli

HNRPC Blocking Peptide - 33R-4848 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

hnRNP-C1/C2 / HNRNPC (1-293, His-tag) - AR09905PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

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