HNRNPC

Gene Symbol HNRNPC
Entrez Gene 3183
Alt Symbol C1, C2, HNRNP, HNRPC, SNRPC
Species Human
Gene Type protein-coding
Description heterogeneous nuclear ribonucleoprotein C (C1/C2)
Other Description heterogeneous nuclear ribonucleoproteins C1/C2|hnRNP C1/C2|nuclear ribonucleoprotein particle C1 protein|nuclear ribonucleoprotein particle C2 protein
Swissprots P07910 Q86U45 Q86SF8 Q59FD3 Q53EX2 D3DS19 Q96IY5 D3DS22 Q9BTS3 Q96HK7 P22628 Q5FWE8 Q96HM4
Accessions CAH05635 EAW66392 EAW66393 EAW66394 EAW66395 EAW66396 EAW66397 EAW66398 EAW66399 EAW66400 P07910 AB209527 BAD92764 AK126950 BAG54408 AK223517 BAD97237 AK225032 AK292619 BAF85308 AK297482 BAG59903 AK298906 BAG61014 AK299923 BAG61758 AK302213 BAG63570 AK312338 BAG35259 AK312382 BAG35300 AL833432 BC003394 AAH03394 BC007052 AAH07052 BC008364 AAH08364 BC008423 AAH08423 BC066932 AAH66932 BC071943 BC089438 AAH89438 BC092433 AAH92433 BC103758 AAI03759 BC108658 AAI08659 BX161480 CAD61934 BX247961 CAD62300 BX247992 CAD62326 D28382 BAA05748 DB449514 HQ258021 ADR82775 M16342 AAA52680 M29063 AAA36576 Z70766 XM_006720125 XP_006720188 XM_011536708 XP_011535010 XM_011536709 XP_011535011 XM_011536710 XP_011535012 XM_011536711 XP_011535013 XM_011536712 XP_011535014 NM_001077442 NP_001070910 NM_001077443 NP_001070911 NM_004500 NP_004491 NM_031314 NP_112604
Function Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. {ECO:0000269|PubMed:12509468, ECO:0000269|PubMed:16010978, ECO:0000269|PubMed:7567451, ECO:0000269|PubMed:8264621}.
Subcellular Location Nucleus. Note=Component of ribonucleosomes.
Top Pathways Spliceosome

hnRNP C1/C2 Antibody - 12392 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using hnRNP C1/C2 Antibody.

hnRNP C1/C2 (4F4) - sc-32308 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
hnRNP C1/C2 (4F4): sc-32308. Western blot analysis of hnRNP C1/C2 expression in HeLa (A), Jurkat (B), THP-1 (C), A-431 (D), K-562 (E) and MEG-01 (F) whole cell lysates.

hnRNP C1/C2 (H-105) - sc-15386 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
hnRNP C1/C2 (H-105): sc-15386. Immunofluorescence staining of methanol-fixed HeLa cells (A) and immunoperoxidase staining of formalin-fixed, paraffin-embedded mouse liver tissue (B) showing nuclear localization.

hnRNP C1/C2 (N-16) - sc-10037 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
hnRNP C1/C2 (N-16): sc-10037. Western blot analysis of hnRNP C1/C2 expression in HeLa (A) and K-562 (B) nuclear extracts.

hnRNP C2 (V-13) - sc-10041 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
hnRNP C2 (V-13): sc-10041. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization

C2 (H-300) - sc-134639 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-hnRNP C1 + C2 (phospho S260) antibody - ab61796 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-hnRNP C1 + C2 (phospho S260) antibody (ab61796) at 1/500 dilutionLane 1 : 293 cell extracts treated with H2O2 (100uM, 15mins)Lane 2 : 293 cell extracts treated with H2O2 (100uM, 15mins) with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-hnRNP C1 + C2 (phospho S260) antibody - ab192219 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-hnRNP C1 + C2 (phospho S260) antibody (ab192219) at 1/5000 dilutionLane 1 : 293 whole cell lysates, treated with H2O2 with antigen-specific peptideLane 2 : 293 whole cell lysates, treated with H2O2Lysates/proteins at 12.5 µg per lane.

Anti-hnRNP C1 + C2 antibody - ab97541 from Abcam

Prices $385.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-hnRNP C1 + C2 antibody (ab97541) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-hnRNP C1 + C2 antibody - ab107124 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-hnRNP C1 + C2 antibody (ab107124) at 1/100 dilution + Jurkat cell line lysates at 35 µg

Anti-hnRNP C1 + C2 antibody - ab61772 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-hnRNP C1 + C2 antibody (ab61772) at 1/500 dilutionLane 1 : extracts from HuvEc cells, treated with EGF (200ng/ml, 5mins) with no peptideLane 2 : extracts from HuvEc cells, treated with EGF (200ng/ml, 5mins) with peptide

Anti-hnRNP C1 + C2 antibody - ab130826 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-hnRNP C1 + C2 antibody (ab130826) at 1 µg/ml + Mouse lung lysates at 10 µg

Anti-hnRNP C1 + C2 antibody [4F4] - ab10294 from Abcam

Prices $397.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4F4
All lanes : Anti-hnRNP C1 + C2 antibody [4F4] (ab10294) at 1/1000 dilutionLane 1 : Nuclear lysate, HEK293A cellsLane 2 : Cytoplasmic lysate, HEK293A cellsLysates/proteins at 30 µg per lane.SecondaryHRP conjugated ImmunoPure Goat Anti-Mouse IgG (H+L) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-hnRNP C1 + C2 antibody [4F4] - ab195988 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4F4

Anti-hnRNP C1 + C2 antibody [55.1_3A9] - ab174704 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 55.1_3A9

Anti-hnRNP C1 + C2 antibody [55.1_3A9] - ChIP Grade - ab128049 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 55.1_3A9
ab128049 at 1/100 staining hnRNP C1+C2 in 4% paraformaldehyde fixed, 0.1% Triton X-100 permeabilized HeLa cells by Immunocytochemistry.

Anti-hnRNP C1 + C2 antibody [EP3034Y] - ab75822 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP3034Y
ab75822 at 1/100 dilution staining hnRNP C1 + C2 in human breast carcinoma by Immunohistochemistry, Paraffin-embedded tissue.

Anti-hnRNP C1 + C2 antibody [EPNCIR152] - ab133607 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPNCIR152
All lanes : Anti-hnRNP C1 + C2 antibody [EPNCIR152] (ab133607) at 1/10000 dilutionLane 1 : HeLa cell lysateLane 2 : MCF7 cell lysateLane 3 : HepG2 cell lysateLane 4 : K562 cell lysateLane 5 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-HNRNPC / HNRNP C Antibody (aa241-290) IHC-plus™ - LS-B7668 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HNRNPC / HNRPC antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7668 concentration 10 ug/ml.

Anti-HNRNPC / HNRNP C Antibody (aa1-142) - LS-C186303 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Cal27 Xenograft using hnRNP C1/C2 antibody at 1:100 dilution.

Anti-HNRNPC / HNRNP C Antibody (clone 4F4) IHC-plus™ - LS-B12099 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 4F4
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-HNRNPC / HNRNP C Antibody - LS-C68188 from LifeSpan Bioscience

Prices $530.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal

Anti-HNRNPC / HNRNP C Antibody (aa80-129) - LS-C30445 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-HNRNPC / HNRNP C Antibody (C-Terminus) - LS-C151220 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HNRNPC / HNRNP C antibody Western Blot of Mouse Lung.

Anti-HNRNPC / HNRNP C Antibody (clone 55.1_3A9) IHC-plus™ - LS-B8725 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 55.1_3A9
Anti-HNRNPC / HNRNP C antibody IHC staining of human skin, epidermis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Search more