| Gene Symbol |
EOGT
|
| Entrez Gene |
285203
|
| Alt Symbol |
AER61, AOS4, C3orf64, EOGT1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
|
| Other Description |
AER61 glycosyltransferase|EGF domain-specific O-linked N-acetylglucosamine transferase|EGF-O-GlcNAc transferase|extracellular O-linked N-acetylglucosamine transferase
|
| Swissprots |
Q6ZTV0 Q6P985 L7X1M5 B4DFH5 A8K2U1 Q5NDL2 Q6MZY0
|
| Accessions |
Q5NDL2 AA709285 AJ868234 CAI30569 AK023140 AK091089 BAG52283 AK123213 AK126187 BAC86479 AK290356 BAF83045 AK294101 BAG57436 AK304102 BAG65005 AL833467 BC028935 AAH28935 BC060887 AAH60887 BX640821 CAE45897 BX648818 DA856791 HQ448550 ADQ33029 KC347596 AGC92970 XM_005264743 XP_005264800 XM_011533599 XP_011531901 XM_011533600 XP_011531902 XM_011533601 XP_011531903 XM_011533602 XP_011531904 XM_011533603 XP_011531905 XM_011533604 XP_011531906 XM_011533605 XP_011531907 NM_001278689 NP_001265618 NM_173654 NP_775925 NR_103826
|
| Function |
Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N- acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains. {ECO:0000269|PubMed:23671640}.
|
| Subcellular Location |
Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}.
|
| Top Pathways |
Other types of O-glycan biosynthesis
|