SF1

Gene Symbol SF1
Entrez Gene 7536
Alt Symbol BBP, D11S636, MBBP, ZCCHC25, ZFM1, ZNF162
Species Human
Gene Type protein-coding
Description splicing factor 1
Other Description mammalian branch point-binding protein|transcription factor ZFM1|zinc finger gene in MEN1 locus|zinc finger protein 162
Swissprots Q969H7 B7Z1Q1 C9JJE2 Q9BW01 Q14819 Q15913 Q92744 Q14818 Q15637 Q8IY00 Q92745 Q9UEI0
Accessions CAA03883 CCO13811 EAW74286 EAW74287 EAW74288 EAW74289 EAW74290 EAW74291 EAW74292 EAW74293 EAW74294 EAW74295 EAW74296 EAW74297 Q15637 AI492561 AK293753 BAH11587 AK296237 BAG58956 AK299705 BAG61606 AK301803 BAG63254 BC000773 AAH00773 BC008080 AAH08080 BC008724 AAH08724 BC011657 BC020217 AAH20217 BC032676 BC034451 BC038446 AAH38446 BC069273 BQ230035 BU624935 BX095574 D26120 BAA05116 D26121 BAA05118 D26122 BAA05119 DC368015 DC370979 EU832634 ACE87725 EU832710 ACE87042 L49345 AAB03514 L49380 AAB04033 Y08765 CAA70018 Y08766 CAA70019 XM_011545244 XP_011543546 XM_011545245 XP_011543547 XM_011545246 XP_011543548 XM_011545247 XP_011543549 XM_011545248 XP_011543550 NM_001178030 NP_001171501 NM_001178031 NP_001171502 NM_004630 NP_004621 NM_201995 NP_973724 NM_201997 NP_973726 NM_201998 NP_973727 NR_033649 NR_033650
Function Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor. {ECO:0000269|PubMed:10449420, ECO:0000269|PubMed:8752089, ECO:0000269|PubMed:9660765}.
Subcellular Location Nucleus.
Tissue Specificity Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart. {ECO:0000269|PubMed:7912130}.

splicing factor 1 (E-9) - sc-365269 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
splicing factor 1 (E-9): sc-365269. Western blot analysis of splicing factor 1 expression in HeLa whole cell lysate.

splicing factor 1 (H-9) - sc-398881 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
splicing factor 1 (H-9): sc-398881. Western blot analysis of splicing factor 1 expression in HeLa (A), U-251-MG (B), Hep G2 (C) and Jurkat (D) whole cell lysates and KNRK (E) and Sol8 (F) nuclear extracts.

splicing factor 1 (H-160) - sc-48792 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
splicing factor 1 (H-160): sc-48792. Western blot analysis of splicing factor 1 expression in non-transfected: sc-117752 (A) and human splicing factor 1 transfected: sc-177973 (B) 293T whole cell lysates.

splicing factor 1 (N-14) - sc-21157 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
splicing factor 1 (N-14): sc-21157. Western blot analysis of splicing factor 1 expression in HeLa whole cell lysate.

splicing factor 1 (YZ-2) - sc-101143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
splicing factor 1 (YZ-2): sc-101143. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon tissue showing nuclear localization.

Anti-splicing factor 1 (phospho S82) antibody - ab59242 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab59242 at 1/50 dilution staining splicing factor 1 in human brain by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunizing peptide.

Anti-splicing factor 1 antibody - ab58077 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Immunofluorescence of  HeLa cells using ab58077 at 10 μg/ml.

Anti-splicing factor 1 antibody - ab189274 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-splicing factor 1 antibody (ab189274) at 1/500 dilutionLane 1 : COLO205 cell extractLane 2 : COLO205 cell extract with synthesized peptide

Anti-splicing factor 1 antibody - ab59263 from Abcam

Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human brain tissue using ab59263 at a dilution of 1/50-1/100. Left hand image - without immunising peptide; right hand image - with immunising peptide.

Anti-splicing factor 1 antibody - ab83057 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-splicing factor 1 antibody (ab83057) at 1 µg/ml (in 5% skim milk / PBS buffer) + transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-splicing factor 1 antibody - ab51084 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Lane 1 : MarkerLane 2 : Anti-splicing factor 1 antibody (ab51084) at 1 µg/mlLane 1 : As aboveLane 2 : HepG2 cell lysate at 10 µg with skim milk/ PBS at 5 %SecondaryLane 2 : HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-splicing factor 1 antibody - ab123389 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-splicing factor 1 antibody (ab123389) at 1/100 dilution + HepG2 cell line lysates at 35 µg

Anti-SF1 Antibody (aa10-25) IHC-plus™ - LS-B3095 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SF1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3095 concentration 10 ug/ml.

Anti-SF1 Antibody (clone 2E12) IHC-plus™ - LS-B4465 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2E12
Anti-SF1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4465 concentration 5 ug/ml.

Anti-SF1 Antibody (aa11-30) - LS-C313004 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SF1 antibody. IHC(F): Rat Spleen Tissue.

Anti-SF1 Antibody (aa215-264) IHC-plus™ - LS-B10256 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SF1 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10256 concentration 10 ug/ml.

Anti-SF1 Antibody (aa48-97) IHC-plus™ - LS-B7622 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SF1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7622 concentration 10 ug/ml.

Anti-SF1 Antibody (aa65-114) IHC-plus™ - LS-B10255 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SF1 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10255 concentration 10 ug/ml.

Anti-SF1 Antibody (aa517-566) IHC-plus™ - LS-B1563 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SF1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1563 concentration 5 ug/ml.

Anti-SF1 Antibody (N-Terminus) - LS-C31720 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
SF1 antibody LS-C31720 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-SF1 Antibody (C-Terminus) - LS-C80404 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-SF1 Antibody (N-Terminus) - LS-C101699 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SF1 antibody LS-C101699 Western blot of Transfected 293T cell lysate.

Anti-SF1 Antibody (aa212-241, APC) - LS-C269074 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SF1 Antibody (aa212-241, AP) - LS-C269075 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SF1 Antibody (aa212-241, Biotin) - LS-C269076 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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