Gene Symbol | SF1 |
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Entrez Gene | 7536 |
Alt Symbol | BBP, D11S636, MBBP, ZCCHC25, ZFM1, ZNF162 |
Species | Human |
Gene Type | protein-coding |
Description | splicing factor 1 |
Other Description | mammalian branch point-binding protein|transcription factor ZFM1|zinc finger gene in MEN1 locus|zinc finger protein 162 |
Swissprots | Q969H7 B7Z1Q1 C9JJE2 Q9BW01 Q14819 Q15913 Q92744 Q14818 Q15637 Q8IY00 Q92745 Q9UEI0 |
Accessions | CAA03883 CCO13811 EAW74286 EAW74287 EAW74288 EAW74289 EAW74290 EAW74291 EAW74292 EAW74293 EAW74294 EAW74295 EAW74296 EAW74297 Q15637 AI492561 AK293753 BAH11587 AK296237 BAG58956 AK299705 BAG61606 AK301803 BAG63254 BC000773 AAH00773 BC008080 AAH08080 BC008724 AAH08724 BC011657 BC020217 AAH20217 BC032676 BC034451 BC038446 AAH38446 BC069273 BQ230035 BU624935 BX095574 D26120 BAA05116 D26121 BAA05118 D26122 BAA05119 DC368015 DC370979 EU832634 ACE87725 EU832710 ACE87042 L49345 AAB03514 L49380 AAB04033 Y08765 CAA70018 Y08766 CAA70019 XM_011545244 XP_011543546 XM_011545245 XP_011543547 XM_011545246 XP_011543548 XM_011545247 XP_011543549 XM_011545248 XP_011543550 NM_001178030 NP_001171501 NM_001178031 NP_001171502 NM_004630 NP_004621 NM_201995 NP_973724 NM_201997 NP_973726 NM_201998 NP_973727 NR_033649 NR_033650 |
Function | Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor. {ECO:0000269|PubMed:10449420, ECO:0000269|PubMed:8752089, ECO:0000269|PubMed:9660765}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart. {ECO:0000269|PubMed:7912130}. |
Human splicing factor 1 full length protein - ab159822 from Abcam
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Human splicing factor 1 protein fragment - ab159823 from Abcam
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SF1 Antibody Blocking Peptide - LS-E3205 from LifeSpan Bioscience
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SF1 Antibody Blocking Peptide - LS-E11834 from LifeSpan Bioscience
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SF1 Antibody Blocking Peptide - LS-E11833 from LifeSpan Bioscience
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SF1 Antibody Blocking Peptide - LS-E13843 from LifeSpan Bioscience
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SF1 Antibody Blocking Peptide - LS-E15151 from LifeSpan Bioscience
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SF1 Antibody Blocking Peptide - LS-E15150 from LifeSpan Bioscience
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Recombinant Human Splicing Factor 1 Protein - H00007536-P01 from Novus Biologicals
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Recombinant Human Splicing Factor 1 Protein - H00007536-Q01 from Novus Biologicals
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SF1-Antibody-Center-Blocking-Peptide - BP14357c from Abgent, a WuXi AppTec company
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SF1 Blocking Peptide - 33R-1432 from Fitzgerald
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SF1 Blocking Peptide - 33R-5763 from Fitzgerald
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SF1 Blocking Peptide - 33R-6645 from Fitzgerald
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Splicing factor 1 (SF1) - H00007536-P01 from Acris Antibodies
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Splicing factor 1 (SF1) - H00007536-Q01-10 from Acris Antibodies
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Splicing factor 1 (SF1) - H00007536-Q01-25 from Acris Antibodies
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SF1 fusion protein - Ag2209 from Proteintech Group
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Recombinant Human SF1, GST-tagged - SF1-2610H from Creative Biomart
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Recombinant Human SF1, GST-tagged - SF1-2609H from Creative Biomart
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SF1 (P76) Peptide - BS1593P from Bioworld Technology
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Recombinant Human Splicing factor 1(SF1) - CSB-YP021120HU CSB-EP021120HU CSB-BP021120HU CSB-MP021120HU from Cusabio
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SF1 (pS82) Blocking Peptide - abx161728 from Abbexa
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Splicing factor 1 (SF1) (transcript variant 3) - TP305846 from Acris Antibodies
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Splicing Factor 1 Recombinant Protein Antigen - NBP1-86835PEP from Novus Biologicals
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