Il4r

Gene Symbol Il4r
Entrez Gene 25084
Alt Symbol Il4ra
Species Rat
Gene Type protein-coding
Description interleukin 4 receptor
Other Description IL-4 receptor subunit alpha|IL-4R subunit alpha|IL-4R-alpha|IL-4RA|interleukin 4 receptor, alpha|interleukin-4 receptor alpha chain|interleukin-4 receptor subunit alpha
Swissprots Q63257 Q9WTM8 Q9R1W8
Accessions EDM17513 EDM17514 EDM17515 EDM17516 Q63257 AB015746 BAA78337 AB015747 BAA78338 AW527353 BQ204155 X69903 CAA49528 XM_006230215 XP_006230277 XM_006230216 XP_006230278 XM_008759862 XP_008758084 XM_008759863 XP_008758085 XM_008759864 XP_008758086 NM_133380 NP_596871
Function Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2 (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Isoform 2 is expressed in kidney, spleen, lung and liver.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Inflammatory bowel disease (IBD)

Rat IL4R / Il4ra HEK293 Cell Lysate (WB positive control) - 80198-R08HL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Rat

Rat IL4R / Il4ra HEK293 Cell Lysate (WB positive control) - 80198-R02HL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Rat

Rat IL4R Human Cells Transfected Lysate (positive control) (denatured) - orb174191 from Biorbyt

Category Cell Lysate
Prices $425.00
Sizes 300 μg
Species Rat

Rat IL4R Human Cells Transfected Lysate (positive control) (denatured) - orb174615 from Biorbyt

Category Cell Lysate
Prices $604.00
Sizes 300 μg
Species Rat
Search more