| Gene Symbol |
CLDN18
|
| Entrez Gene |
51208
|
| Alt Symbol |
SFTA5, SFTPJ
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
claudin 18
|
| Other Description |
claudin-18|surfactant associated 5|surfactant associated protein J|surfactant, pulmonary associated protein J
|
| Swissprots |
P56856 A5PL21 Q96PH4
|
| Accessions |
BAF98890 EAW79092 EAW79093 EAW79094 P56856 AF221069 AAF26448 AF349452 AAL15637 AK098474 AK298103 BAG60388 AY102073 AY358479 AAQ88843 BC063845 BC142708 AAI42709 BC146668 AAI46669 BM785703 NM_001002026 NP_001002026 NM_016369 NP_057453
|
| Function |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.
|
| Subcellular Location |
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Concentrated at the cell-cell borders of epithelial cells.
|
| Top Pathways |
Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C
|